Amines 1.3- diaminopropane

EOF reversal Surfactants SDS, CTAB, Brij, Tween, quaternary amines, diaminopropane, diaminobutane, Polybrene ... 

The "zip-reaction (U. Kramer, 1978, 1979) leads to giant macrocycles. Potassium 3- ami-nopropyl)amide = KAPA ( superbase ) in 1,3-diaminopropane is used to deprotonate amines. The amide anions are highly nucleophilic and may, for example, be used to transam-idate carboxylic amides. If N- 39-atnino-4,8,12,16,20,24,28,32,36-nonaazanonatriacontyl)do-decanolactam is treated with KAPA, the amino groups may be deprotonated and react with the macrocyclic lactam. The most probable reaction is the intramolecular formation of the six-membered ring intermediate indicated below. This intermediate opens spontaneously to produce the azalactam with seventeen atoms in the cycle. This reaction is repeated nine times in the presence of excess KAPA, and the 53-membered macrocycle is formed in reasonable yield. 

Unit cells of pure cellulose fall into five different classes, I—IV and x. This organization, with recent subclasses, is used here, but Cellulose x is not discussed because there has been no recent work on it. Crystalline complexes with alkaU (50), water (51), or amines (ethylenediamine, diaminopropane, and hydrazine) (52), and crystalline cellulose derivatives also exist. Those stmctures provide models for the interactions of various agents with cellulose, as well as additional information on the cellulose backbone itself. Usually, as shown in Eigure la, there are two residues in the repeated distance. However, in one of the alkah complexes (53), the backbone takes a three-fold hehcal shape. Nitrocellulose [9004-70-0] heUces have 2.5 residues per turn, with the repeat observed after two turns (54). 

Diaminopropane Processes. 1,2-Propylenediamine can be produced by the reductive amination of propylene oxide (142), 1,2-propylene glycol [57-55-6] (143), or monoisopropanolamine [78-96-6] (144). 1,3-Propanediol [504-63-2] can be used to make 1,3-diaminopropane (143). Various propaneamines are produced by reducing the appropriate acrylonitrile—amine adducts (145—147). Polypropaneamines can be obtained by the oligomerization of 1,3-diaminopropane (148,149). 

Diaminoethane, diaminopropane, 1-amino-2-propanol, diami-nobutane, diaminopentane. u-decylamine 25 m CPWAX column for amines and diamines at 135°. 

An inducible primary amine dehydrogenase in a strain of Mycobacterium convolutum had diverse degradative capability with a broad specificity, and was involved in the degradation of 1- and 2-aminopropane and 1,3-diaminopropane. The products were assimilated by the methylmalonate pathway, or by formation of C2 + Cj fragments (Cerniglia and Perry 1975). 

Species of Pseudomonas can utilize the a,(i)-diamines putrescine, spermidine, and spermine as sources of carbon and nitrogen, and putrescine can be produced from the secondary amine spermidine together with 1,3-diaminopropane (Dasu et al. 2006). Putrescine (1,4-diaminobutane) is an intermediate in the arginine decarboxylase (ADC) pathway of L-arginine degradation, which is described later, and can be degraded, by two pathways ... 

The current work indicates that sulfided platinum catalysts are, in general, more active and selective than Pt, Pd, or sulfided Pd catalysts for reductive alkylation of primary amines with ketones. The choice of the catalyst preparation parameters, especially the support, plays a major role in determining the performance of the catalyst. Diamines, especially of lower molecular weight, tend to react with ketones even at room temperature to form heterocycles such as imidazolidine, diazepanes, and pyrimidines. Hence, a continuous reactor configuration that minimizes the contact between the amine and the ketone, along with a highly active catalyst is desired to obtain the dialkylated product. In general, sulfided Pt appears to be more suited for the reductive alkylation of ethylenediamine while unsulfided Pd or Pt may also be used if 1,3-diaminopropane is the amine. 

By judicious choice of reaction conditions an acyclic Ni11 complex (784) could be isolated, which serves as a valuable starting material for the preparation of unsymmetrical and mixed metal complexes by subsequent reaction with various amines. Also, a symmetrical Schiff base macrocycle of larger size has been obtained as a minor byproduct upon condensation of (784) with 1,3-diaminopropane. The resulting Ni11 complex (785) is again bimetallic, although room to bind four metal ions is in principle available.1367... 

The combination of pyridine and aliphatic nitrogen donors creates an intermediate ligand field which has yielded a long list of spin crossover systems [2]. Recently, Kahn et al. obtained two new tetradentate ligands in which two 2-pyridylmethyl groups replace two hydrogen atoms on the same amine function in 1,2-diaminoethane and 1,3-diaminopropane (4, 5) [5-6]. 

A variety of alkyl amines B, including 1-propylamine, ethylene diamine, 1,3-diaminopropane, and (7 )-l-amino-2-propanol have been used as reactants. The guest exchange kinetic results are reported in Table 13. The presence of more than one reacting [/3-CD-H-A] structure is observed with A = DOPA and penicillamine. The results have been rationalized in terms of specific interactions in the relevant inclusion complexes which determine their structure and relative stability. 

A number of amines have been investigated for their suitability as polymerisation initiators, including aliphatic amines (such as butylamine [17] and 1,3-diaminopropane [18]), polymer supported amines (such as cross-linked aminomethyl polystyrene [CLAMPS], Fig. 1, giving rise to immobilised polyamino acids [19]) and resin-bound amines. 

The nitration of 1,1,2,2-tetraiodoethylene (182) with 90% nitric acid provides 1,1-diiododinitroethylene (183) in good yield. Baum and co-workers studied the chemistry of 1,1-diiododinitroethylene and found that displacement of the two vinylic iodide groups is effected by treatment with simple aliphatic amines, diamines and anilines to give 1,1-diamino-2,2-dinitroethylenes in excellent yield. Cyclic products are obtained from the reaction of 1,1-diiododinitroethylene with 1,2-diaminoethane (ethylenediamine), 1,3-diaminopropane and 1,4-diaminobutane. The spirocycle (184) is synthesized from the reaction of 1,1-diiododinitroethylene (183) with 2,2-bis(methylamino)-l,3-diaminopropane. 

Amine quantification is usually accomplished using the internal standard method. Different amines have been used for this purpose 1,7-diaminoheptane [282], 1,3-diaminopropane [287], and benzylamine [311]. 

There appears for A1P0,-15 (refs. 22,23), GaPO,-C7 and AlAsO,-7 an interesting phenomenon that during synthesis the amines (1,4-diaminopropane,PrNH2 and DMA respectively) are fragmentized into NH7, which enters the MXO, framework as a template. No satisfactory explanation for this has been reported to date. 

Azetidines are often synthesized by reacting 1,3-dihalogenopropanes with an amine (ammonia gives poor yields), or from propane-1,3-diamines where one A-substituent can function as a leaving group. A reaction of the latter type is used to synthesize azetidine from A,A-bis(toluenesul-fonyl)-l,3-diaminopropane in two steps, the last being a reductive A-de-toluenesulfonation, caused by adding sodium to naphthalene in an inert solvent (Scheme 8.5). 

Here pn is 1,2-diaminopropane and bn is 2,3-diaminobutane. Decomposition of the amine cation radicals obtained by photooxidation of the ligands en, bn, and pn have been discussed by Moeller. The products of Co(en)33+ photolysis can be satisfactorily explained by postulating that carbon-carbon bondbreaking is the principal step in decomposition of the cation radical H2NCH2CH2NH2t.58 Presuming a similar mechanism to obtain in photoreduction of Co(pn)33+, there are then two possible reaction pathways leading to different products. 

Complexes [VL3]X2 (L = en, 1,2-diaminopropane, 1,3-diaminopropane X = C1, Br, I) and [V(dien)2]X2 were prepared by mixing ethanolic solutions of amine and of vanadium(II) halide. The magnetic moments (3.66-3.91 BM) and electronic spectra were typical of octahedral vanadium(II) and there was no halogen coordination.65... 

Although earlier attempts to isolate chromium(II) complexes of various bidentate amines from aqueous solutions produced chromium(III) complexes and hydrogen, the predominantly non-aqueous methods outlined in Scheme 10 provide complexes of ethylenediamine (en), 1,2-diaminopropane (pn), 1,3-diaminopropane (tmd), l,2-diamino-2-methylpropane (dmp), jVjA-dimethylethylenediamine (NNdmn) and N, N -dimethylethylenediamine (NN dmn) (Table 11). In general, ethanol is a suitable solvent but with some amines it is necessary to dehydrate the halide with 2,2-dimethoxypropane (DMP) and dry the ethanol carefully to prevent hydrolysis and oxidation. 

As an illustrative example, the monomers used for the preparation of a typical polyacrylamide support (Pepsyn) and its schematic representation are sketched in Figure 2.6. The ester functionality, obtained by copolymerization with A-acryloylsarco-sine methyl ester, can be used as the attachment point for a suitable linker. This can be achieved by aminolysis with ethylenediamine, followed by acylation of the resulting primary amine with 3-(4-hydroxymethyl)phenylpropionic acid [163] or other linkers. Similar supports have been prepared by copolymerization of protected allylamine [37] or lV-(acryloyl)-l,3-diaminopropane [173] with V,lV-dimethylacrylamide and... 

V,/V -bis(acryIoyI)-l,3-diaminopropane. Amine deprotection after polymerization leads directly to the functionalized support. 

Since their discovery in 1954 by Tarantola (93), more than 30 amines have been identified in wine. Among the most common are butylamine, Cad, Try, ethanolamine, 1,3-diaminopropane,... 

The reductive amination of a substituted 1,3-diaminopropane with glyoxal provided the saturated 1,4-diazepine derivatives, which have been used as intermediates in the synthesis of a number of biologically active compounds <1998T10671, 20020PD28>. This process is related to the previously established method for the synthesis of 1,4-diazepin-2-ones that relies upon the combination of glyoxal, or its bis-bisulfite, with a 1,3-diaminopropane derivative under nonreducing conditions <2001JOC5822>. 

Cyclic ketene acetals can also react with amines to give 1,1-enediamines with elimination of ethylene glycol76. Treatment of 2-[(methoxycarbonyl)cyanomethylene]-1,3-dioxolane (38) with 1,3-diaminopropane or with 4,5-dimethyl-1,2-phenylenediamine gives the hexahydropyrimidine and the benzimidazoline derivatives 39 and 40, respectively (equation 11). Similarly to the reaction of ketene dithioacetals with amines, the reaction between ketene acetals and amines proceeds via monoamino-substituted intermediates and ketene 7V,Oacetals can be isolated when one molar amine is used72. 

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