Alzheimer s disease, amyloid

Izumi, R., Yamada, T., Yoshikai, S., Sasaki, H., Hattori, M., Sakaki, Y. (1992). Positive and negative regulatory elements for the expression of the Alzheimer s disease amyloid precursor-encoding gene in mouse. Gene 112, 189-195. [Pg.455]

Salbaum, J.M., Weidemann, A., Masters, C.L., Beyreuther, K. (1989). The promoter of Alzheimer s disease amyloid A4 precursor gene. Prog. Clin, Biol. Res. 317, 277-283. [Pg.459]

Harper JD, Lieber CM, Lansbury PT Jr. Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer s disease amyloid-beta protein. Chem Biol 1997 4 951-959. [Pg.277]

Hope, J., Shearman, M. S., Baxter, H. C., Chong, A., Kelly, S. M., and Price, N. C. (1996). Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer s disease amyloid peptide, A [S 25-35. Neurodegeneration 5, 1-11. [Pg.208]

Mason, R. P., Estermyer, J. D., Kelly, J. F., and Mason, P. E. (1996). Alzheimer s disease amyloid // peptide 25-35 is localized in the membrane hydrocarbon core X-ray diffraction analysis. Biochem. Biophys. Res. Commun. 222, 78-82. [Pg.211]

Curtain, C.C., Ali, F., Volitakis, I., Cherny, R.A., et al. (2001) Alzheimer s disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits, J. Biol. Chem., 276, 20466-20473. [Pg.320]

Phiel, C.J., Wilson, C.A., Lee, V.M., Klein, P.S. (2003) GSK-3alpha regulates production of Alzheimer s disease amyloid-beta peptides. Nature, 423, 435-439. [Pg.332]

Marambaud, P., Zhao, H., Davies, P. (2005) Resveratrol promotes clearance of Alzheimer s disease amyloid- 3 peptides. J. Biol. Chem., 280, 37377-37382. [Pg.344]

Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Msters, C. L., Grzeschik, . H., Multhaup, G., Beyreuther, K., and Muller-Hill, B. (1987). The precursor of Alzheimer s disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736. [Pg.69]

Paresce DM, Ghosh RN, Maxfield FR. 1996. Microglial cells internalize aggregates of the Alzheimer s disease amyloid beta-protein via a scavenger receptor. Neuron 17(3) 553-565. [Pg.132]

Evin G, Zhu A, Holsinger RM, Masters CL, Li QX. Proteolytic processing of the Alzheimer s disease amyloid precursor protein in brain and platelets. J Neurosci Res 2003 74(3) 386—392. [Pg.128]

Paik S R, Lee J-H, Kim D-H, et al. 1997. Aluminum-induced structural alterations of the precursor of the non-alphabeta component of Alzheimer s disease amyloid. Arch Biochem Biophys 344 325-334. [Pg.342]

Wolf BA, Wertkin AM, Jolly YC, et al. Muscarinic regulation of Alzheimer s disease amyloid precursor protein secretion and amyloid p-protein production in human neuronal NT2N cells. J Biol Chem 1995 270 4916-4922. [Pg.478]

The consensus opinion is that, regardless of the causes of Alzheimer s disease, amyloid-P proteins are deposited in the brain and, together with tau proteins, form... [Pg.219]

The precursor of Alzheimer s disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736. [Pg.275]

Weidemann, A., Paliga, K., Durrwang, U., Reinhard, F.M., Schuckert, O., Evin, G. and Masters, C.L. (1999) Proteolytic processing of the Alzheimer s Disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases, J. Biol. Chem. 274, 5823. [Pg.353]

Pai esce DM, Chung H, Maxfield FR (1997) Slow degi adadoii of aggi egates of die Alzheimer s disease amyloid beta-protein by microglial cells. J Biol Chem 272 29390-29397. [Pg.359]

Wliite AR, Du T, Laughton KM, Volitakis I, Sharpies RA, Hoke DE, Holsinger RM, Evin G, Cherny RA, Hill AF, Barnham KJ, Li QX, Bush AI, Masters CL (2006) Degradation of the Alzheimer s disease amyloid beta peptide by metal-dependent up-regulahon of metalloprotease acti vity. A quantitative study. J Biol Chem 281(26) 17670-17680. [Pg.361]

Keywords Active vaccination Alzheimer s disease Amyloid Amyloid precursor protein Antibody titer Beta-pleated sheet Cerebral amyloid angiopathy Dementia Immunotherapy Monoclonal antibody Passive vaccination Senility... [Pg.631]

Keywords Active imimnizadon Adenovims Adeno-associated vkus Alzheimer s disease Amyloid-beta Chemokine Cytokine Lendvirus Herpes simplex vims Isotypes Parkinson s disease Passive immunizadon Single-chain andbodies Thl cells Th2 cells Transgene Vector... [Pg.709]

M. I. Brazil et al., effects of incorporation of immunoglobulin G and complement component Clq on uptake and degradation of Alzheimer s disease amyloid fibrils by microglia, J. Biol. Chem. 275 (2000) 16941-16947. [Pg.179]

Walter, M.F. Mason, P.E. Mason, R.P. Alzheimer s disease amyloid p peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions. Biochem. Biophys. Res. Commun. 1997, 233, 760-764. [Pg.154]

Sauder JM, Arthur JW, Dunbrack RL Jr. 2000. Modeling of substrate specificity of the Alzheimer s disease amyloid precursor protein beta-secretase. J. Mol. Biol. 300 241 18... [Pg.580]

Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Holter SM et al (2011) Telomere shortening reduces Alzheimer s disease amyloid pathology in mice. Brain 134 2044-2056... [Pg.523]

Keywords Alzheimer s disease Amyloid Copper Clioqninol MPAC... [Pg.108]

Rowan MJ et al (2007) Synaptic memory mechanisms Alzheimer s disease amyloid beta-peptide-induced dysfunction. Biochem Soc Trans 35(Pt 5) 1219-1223... [Pg.55]

Narindrasorasak, S., Lowery, D.E., Altman, R.A., Gonzalez, D.P., Greenberg, B.D., and Kisilevsky, R. (1992). Characterization of high affinity binding between laminin and Alzheimer s disease amyloid precursor proteins. Lab. Invest. 67, 643-652. [Pg.268]

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