Alopecia

Both transient and persistent hair loss have been associated with valproate use. Patients with valproate-induced alopecia may benefit from zinc supplementation, at a dose of 22.5 mg/day (Hurd et al. 1984). 

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The usual symptoms in human thaHotoxicosis resulting from acute, subacute, or chronic intoxication are generaHy the same. Common symptoms include nausea, vomiting, abdominal coHc, pain in legs, nervousness and irtitabHity, chest pain, gingivitis or stomatitis, and anorexia. Alopecia (hair loss) does not always occur, especiaHy in cases of mass intake of thallium and low resistance where the patient may die before the occurrence of hair loss. 

Tb allium intoxication during the first trimester of pregnancy can cause skeletal deformities, alopecia, rash, low birth weight, and premature birth (38). 

USP (Oncovin) vindesine sulfate [59917-39 ] C43H55N5O7 -H2S0 852.01 (50) chil-dren lymphocytic leukemia Hodgkin s disease non-Hodg-kin s lymphomas Wilm s tumor neuroblastoma rhabdomyosarcoma, investigational dmg (paresthesias, foot drop, double vision, etc) constipation ileus alopecia leu-kopenia (occasional) ... 

Vinorelbine) taxol [33069-62 ] C47H51NO14 853.92 (52) nonsmaH cell lung cancer investigational dmg alopecia neutropenia ... 

Alopecia Alopecia is the loss of hair. Acute or chronic exposure to some chemicals may result in the temporary or permanent loss of hair. 

Dacarbazine is the most active compound used for treating metastatic melanoma. It is also combined with anthracyclines and other cytostatics in the treatment of different sarcomas and Hodgkin s disease. Dacarbazine may cause severe nausea and vomiting. Myelosuppres-sion results in leukopenia and thrombocytopenia. Alopecia and transient abnormalities in renal and hepatic function also occur. 

Systemic treatment of 13-cis retinoic acid frequently leads to cheilitis and eye irritations (e.g., unspecific cornea inflammation). Also other symptoms such as headache, pruritus, alopecia, pains of joints and bone, and exostosis formation have been reported. Notably, an increase of very low density lipoproteins and triglycerides accompanied by a decrease of the high density lipoproteins has been reported in 10-20% of treated patients. Transiently, liver function markers can increase during oral retinoid therapy. Etretinate causes the side effects of 13-cis retinoid acid at lower doses. In addition to this, generalized edema and centrilobulary toxic liver cell necrosis have been observed. 

MTX is a potentially toxic dmg that is also used in the treatment of malignancies and psoriasis. Nausea, vomiting, a decreased platelet count, leukopenia (decreased white blood cell count), stomatitis (inflammation of the oral cavity), rash, pruritus, dermatitis, diarrhea, alopecia (loss of hair), and diarrhea may be seen with the administration of this dmg. 

The principal adverse reaction associated with warfarin is bleeding, which may range from very mild to severe. Bleeding may be seen in many areas of the body, such as the bladder, bowel, stomach, uterus, and mucous membranes. Other adverse reactions are rare but may include nausea, vomiting, alopecia (loss of hair), urticaria (severe skin rash), abdominal cramping, diarrhea, rash, hepatitis (inflammation of the liver), jaundice (yellowish discoloration of the skin and mucous membranes), and blood dyscrasias (disorders). 

Anemia, proteinuria, nausea, vomiting, fever, rash, leukopenia, neutropenia, thrombocytopenia, diarrhea, constipation, alopecia Bone marrow depression, hyperuricemia, hepatotoxicity, skin rash... 

Nausea, skin rash, pruritus, stomatitis, vomiting, anemia, leukopenia, neutropenia, arthralgia, alopeda, asthenia, fever, infections Diarrhea, nausea, vomiting, flushing, myalgia, arthralgia, fever, peripheral neuropathy, opportunistic infections Leukopenia, nausea, vomiting, paresthesias, malaise, weakness, mental depression, headache, hypertension, alopecia, diarrhea, constipation... 

Nausea, vomiting, anorexia, diarrhea, constipation, alopecia, granulocytopenia... 

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