Allergic Immune Responses

Local immune responses [51, 108], allergic immune responses [109, 110], and systemic immune suppression [82, 83] have been reported in vivo after exposure to CNTs. 

Granum, B. and Lovik, M. (2002) The effect of particles on allergic immune responses. Toxicological Sciences, 65 (1), 7-17. 

Nygaard, U.C. et al. (2009) Single-walled and multi-walled carbon nanotubes promote allergic immune responses in... 

Regulatory Effects of Histamine and Histamine Receptor Expression in Human Allergic Immune Responses... 

Winkler B, Baier B, Wagner S, Repa A, Scheiner O, Kraft D, Wiedermann U Mucosal tolerance as therapy of type I allergy Intranasal application of recombinant Bet v 1, the major birch pollen allergen, leads to the suppression of allergic immune responses and airway inflammation in sensitized mice. Clin Exp Allergy 2002 32 30-36. 

The serum anti-OVA-specific IgE is significantly decreased only with an increased n-3/n-6 ratio. Both IgE and IgGj are negatively correlated with n-3 fatty acid intakes (r = -0.7585, P = 0.0001 for IgE and r = -0.3974, P = 0.0181 for IgGj by Pearson correlation). Thus, these data suggest that consumption of n-3 fatty acids might be beneficial for alleviation of Th-2-related allergic immune responses. 

To better understand the pathogenesis of human asthma, a variety of experimental approaches using murine models of allergic pulmonary inflammation have been developed. In murine models of human asthma, it is apparent that initiation of the allergic immune response is T-lymphocyte dependent (1,2). However, the predominant direct mediator(s) of allergic inflammation identified in these murine... 

Herz U, Schnoy N, Borelli S, Weigl L, Kasbohrer U, Daser A, Wahn U, Kottgen E, Renz H. A human-SCID mouse model for allergic immune response bacterial superantigen enhances skin inflammation and suppresses IgE production. J Invest Dermatol 1998 110(3) 224-231. 

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