Alcohol misuse

Depression occurring as part of bipolar disorder may be severe and accompanied by ideas of guilt and hopelessness, an inability to function at work because of poor concentration and psychomotor retardation or agitation, poor judgement and suicidal ideation. The lifelong risk of suicide in people with this condition is as high as 15%. Factors associated with suicide risk include alcohol misuse, marital separation or divorce, living alone and unemployment, and these are all common secondary consequences of the illness. 

Kokavec A and Crowe SF (1999). A comparison of cognitive performance in binge versus regular chronic alcohol misusers. Alcohol and Alcoholism, 34, 601-608. 

Cirrhosis A liver disease commonly associated with chronic alcohol misuse and characterised by the replacement of once-healthy hepatocytes with abnormal connective tissue. 

Korsakoff s syndrome A dementia commonly associated with chronic alcohol misuse. 

Wernicke s encephalopathy A neurological condition characterised by visual disturbances, motor dysfunction and confusion which, like Korsakoff s syndrome, is commonly associated with long-term alcohol misuse. 

England - Department of Health (DOH) Alcohol Misuse Information. Online. Available HTTP alcohol/index.htm> (accessed ... 

The strongest traditions of inpatient detoxification relate mainly to alcohol misuse, in which the withdrawal syndrome is inherently more dangerous than that from opiates, and the avoidance of withdrawal complications in standard treatment may be the prime consideration in selecting admission. (In drug misuse, as we shall see in subsequent chapters, indications for admission increasingly relate to new developments, such as rapid... 

Sometimes benzodiazepine or alcohol misuse, and often antidepressant prescribing... 

Can remain a mild disease but alcohol misuse much worsens the prognosis... 

A number of tasks can be identified which community teams hold in common whether their clients are the mentally handicapped, drug or alcohol misusers. Not every team would necessarily see every task identified as part of their role, and the emphasis laid on particular tasks will vary from team to team and sometimes within a team itself. It has already been noted that as teams develop the nature of their roles may also change. 

Q6 Other conditions that could be confused with anxiety include endocrine disorders such as thyroid problems and hypoglycaemia, autonomic disorders, drug/alcohol misuse and other CNS disorders such as panic disorder. 

Alcohol is chiefly important in medicine because of the consequences of its misuse/abuse. Alcohol misuse is a social problem with pharmacological aspects, which latter are discussed here. The history of alcohol is part of the history of civilisation ever since Noah made his epoch-making discovery. ... 

Perkins, H. W. (2002). Social norms and the prevention of alcohol misuse in collegiate contexts. Journal of Studies on Alcohol,... 

Rodriguez-Martin JL, Qizilbash N, and Lopez-Arrieta JM (2001) Thiamine for Alzheimer s disease. Cochrane Database of Systematic Reviews 2 CD001498. Thomson AD (2000) Mechanisms of vitamin deficiency in chronic alcohol misusers and the development of the Wernicke-Korsakoff syndrome. Alcohol Alcoholism 35(Suppl 1) 2-7. 

Thompson AD. Mechanisms of vitamin deficiency in chronic alcohol misuse and the development of the Wernicke-Korsakoff syndrome. Alcohol Alcohol 2000 35 Suppl 1 2-7. 

HPLC measurement of CDT is routinely used in hospital and research laboratories as a way to detect chronic alcohol misuse. The first HPLC method for the quantification of iron-saturated tiansferrin glycoforms was introduced in 1993,and was based on anion-exchange chromatographic separation of the different glycoforms by salt gradient elution followed by photometric detection. Since then, several variations of the original method have been published ,44 8 number of commercial HPLC assays for CDT have been introduced. ... 

The CDG-I pattern resembles that observed after chronic alcohol consumption, albeit the relative increases were much higher in CDG-Ia (Figure 6.4). However, because CDG testing is typically performed at young age, there is usually no risk of false-positive results due to alcohol misuse. Furthermore, the CDG patterns are clearly distinguishable from those observed with the most common genetic transferrin variants, which may cause falsely high or low values with the minicolumn immunoassays for CDT. 

J. Keating, C. Cheung, T.J. Peters and R.A. Sherwood, Carbohydrate deficient transferrin in the assessment of alcohol misuse absolute or relative measurements A comparison of two methods with regard to total transferrin concentration, Clin. Chim. Acta, 272, 159-169 (1998). 

The policy must prohibit the employer from taking adverse action against a driver for making a voltmtary admission of alcohol misuse or drug use. 

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