Misuse, abuse

Mi sbildung,/. malformation deformity, missbilligen, v.t. disapprove of, oppose. Missbrauch, m. misuse, abuse, missen, v.t. miss dispense with. 

Marks J The Benzodiazepines Use, Misuse, Abuse. Lancaster, England, MTP Press, 1978... 

Klein E, Uhde TW, Post RM Preliminary evidence for the utility of carbamazepine in alprazolam withdrawal. Am J Psychiatry 143 235—236, 1986 Kouyanou K, Pither CE, Wessely S Medication misuse, abuse and dependence in chronic pain patients. J Psychosom Res 43 497-304, 1997 Kryspin-Exner K [Misuse of bezodiazepine derivatives in alcoholics] (German). Br J Addict Alcohol Other Drugs 61 283-290, 1966 Kryspin-Exner K, Demel 1 The use of tranquilizers in the treatment of mixed drug abuse. Int J Clin Pharmacol Biopharm 12 13-18, 1973... 

Low K, Crestani F, Keist R, et al Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290 131-134, 2000 Luddens H, Pritchett DB, Kohler M, et al Cerebellar GABAA receptor selective for a behavioural alcohol antagonist. Nature 346 648—651, 1990 LupoloverY, Safran AB, Desangles D, etal Evaluation ofvisual function in healthy subjects after administration of Ro 15-1788. Eur J Clin Pharmacol 27 505-507, 1984 Maher JF, Schreiner GE, Westervelt FB Jr Acute glutethimide intoxication 1. clinical experience (twenty-two patients) compared to acute barbiturate intoxication (sixty-three patients). Am J Med 33 70-82, 1962 Marks J The Benzodiazepines Use, Overuse, Misuse, Abuse. Baltimore, MD, University Park Press, 1978... 

Oxycodone can be abused in a manner similar to other opioid agonists, legal or illicit. Consider this when prescribing or dispensing oxycodone CR tablets in situations where there is concern about an increased risk of misuse, abuse, or diversion. 

Freevibe.com. Misuse, Abuse, and Addiction. Available online at http //www.freevibe.com/Drug Facts/prescription misuse-abuse.asp. Accessed June 2,2006. 

Q7 Laxatives are often misused/abused, for example in slimming disorders, to increase gut transit rate and so limit absorption of foods. Side effects which may occur include flatulence, and abdominal distension or discomfort with bulk-forming and osmotic laxatives. Other adverse effects may include diarrhoea, nausea, vomiting, weakness, dehydration and electrolyte imbalances, for example hypokalaemia. The most prominent side effect of the powerful stimulant/irritant laxatives is abdominal cramping, which is due to increased peristalsis. 

Alcohol is chiefly important in medicine because of the consequences of its misuse/abuse. Alcohol misuse is a social problem with pharmacological aspects, which latter are discussed here. The history of alcohol is part of the history of civilisation ever since Noah made his epoch-making discovery. ... 

TABLE 4.2 Commonly Misused/Abused Drugs as Reported by the National Surveillance Agency Drug Abuse Warning Network (DAWN)... 

Use, Overuse, Misuse, Abuse." University Park Press, Baltimore, MD, L978. 

In-use tests, etc. (i.e. checking possible misuse, abuse by patient or user). 

Abuse liability is the potential for a drug to produce positive effects that will reinforce a pattern of misuse, abuse, or diversion. To date, there is no evidence that the naltrexone component of combined morphine/ naltrexone will prevent or deter abuse. Novel abuse liability trials have been developed to assess the effects of combined morphine/naltrexone when tampered with. The pharmacodynamic effect of naltrexone in the setting of crushed morphine/naltrexone capsules was examined in two clinical trials an oral and an intravenous abuse liability trial [8]. These were conducted in nondependent recreational opioid abusers, as dependent, daily or habitual users would probably experience a withdrawal syndrome when exposed to the naltrexone component with crushed morphine/ naltrexone capsules. 

Abuse all opioids have associated risk of misuse, abuse, addiction, and diversion. Evaluations prior to prescribing opioids should include (a) proper assessment of the patient, (b) proper prescribing practices, and (c) periodic re-evaluation of therapy,... 

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