Airborne exposure guidelines

No specific exposure levels have been reported and there are no airborne exposure guidelines. The effects in humans are not known however, excessive exposure may result in similar effects to what was observed in rats. 

Environmer ed LC50 (fathead minnow, 96 h) 1.2 mg/l PrecaMm Wear chemical goggles, PVC gloves when airborne exposure guidelines and/or comfort levels may be exceeded, use an approved air-purifying respirator... 

Acute Exposure Guideline Levels for Selected Airborne Chemicals... 

In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology the Subcommittee on Acute Exposure Guideline Levels, which prepared this report. This report is the first volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals. It reviews the appropriateness of the AEGLs for four chemicals for their scientific validity, completeness, and consistency with the NRC guideline reports. 

NRC (National Research Council). In press. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Airborne Chemicals. Washington, DC National Academy Press. 

AEGL Acute Exposure Guideline Levels describe the risk from single, nonrepetit-ive exposures to airborne chemicals in a once-in-a-lifetime event. They represent... 

Threshold Limit Value Airborne concentrations of substances devised by the ACGIH that represent conditions under which it is believed that nearly all workers maybe exposed day after day with no adverse effect. TLV s are advisory exposure guidelines, not legal standards, based on evidence from industrial experience, animal studies, or human studies when they exist. There are three different types of TLV s Time Weighted Average (TLV-TWA) Short Term Exposure Limit (TLV-STEL) and Ceiling (TLV-C). (See also PEL)... 

Airborne Exposure Limits (AEL) The permissible airborne exposure concentration for VX for an 8-hour workday of a 40-hour work week is an 8-hour time weighted average (TWA) of 0.00001 mg/m3. This value can be found in DA Pam 40-8, Occupational Health Guidelines for the Evaluation and Control of Occupational Exposure to Nerve Agents GA, GB, GD, and VX. To date, however, the Occupational Safety and Health Administration (OSHA) has not promulgated a permissible exposure concentration for VX. 

AIRBORNE EXPOSURE LIMIT (REL) The AEL for HD is 0.003 mg/m3 as proposed in the USAEHA Technical Guide No. 173, Occupational Health Guidelines for the Evaluation and Control of Occupational Exposure to Mustard Agents H, HD and HT. No individual should be intentionally exposed to any direct skin or eye contact. 

This report is the second volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals. AEGL reports for aniline, arsine, monomethylhydrazine, and dimethylhydrazine were reviewed in the first volume. AEGL documents for five chemicals—phosgene, propylene glycol dinitrate, 1,1,1,2-tetrafluoroethane, 1,1-dichloro-l-fluoroethane, and hydrogen cyanide—are published as an appendix to this report. The subcommittee... 

A Risk-Management Strategy for PCB-Contaminated Sediments (2001) Acute Exposure Guideline Levels for Selected Airborne Chemicals (4 volumes, 2000-2004)... 

The personnel working in the corrosion laboratory are usually exposed to a variety of chemicals and gases. The monitoring of airborne contaminants is to ensure that potential employee exposures are controlled. It is also useful to monitor chemical exposure of personnel and to compare the levels with chemical exposure guidelines of National Institute for Occupational Safety and Health (NIOSH), Occupational Safety and Health Administration (OSHA) OSHA (29 CFR 910.1450, 29 CFR 1910.1048, 11910.1001-1101, Z9 CFR 1910, subpart Z and National Health Canada). It is also useful to perform a walkthrough check for hazardous chemicals and exposure of personnel to the chemicals, as shown in Figure 3.2. 

Krewski, D., Bakshi, K., Garrett, R., Falke, E., Rusch, G., Gaylor, D. (2004). Development of acute exposure guideline levels for airborne exposures to hazardous substances. Regal. Toxicol. Pharmacol. 39 184-201. 

Various standards and guidelines have been developed for sulfur mustard. These values are applieable to occupational exposures, emergeney planning and response efforts, and remediation efforts. Airborne exposure limits (AELs) and health-based environmental sereening levels (HBESLs) for sulfur mustard have been developed by the US Army (USACHPPM, 1999, 2000). Most health-based criteria for sulfur mustard vapor exposure are based upon protection of the eyes and respiratory traet whieh are the most sensitive targets. 

NRC (National Research Cormcil) (2003). Acute Exposure Guideline Levels for Selected Airborne Chemicals. Suhcommittee on Chronic Reference Doses for Selected Chemical-Warfare Agents, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Cormcil. National Academy Press, Washington, DC. 

Benschop, H.P., Van der Schans, M.J., Langenberg, J.P. (2000). Toxicokinetics of O-ethyl S-(2-diisopropylaminoethyl)me-thylphosphonothioate [( )-VX] in rats, hairless guinea pigs and marmosets - identification of metabolic pathways. Cited in Acute Exposure Guideline Levels for Selected Airborne Chemicals, Vol. 3. The National Academies Press, Washington DC, 2003, 122 pp. 

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