Acute Exposure Guidelines AEGL

United States Environmental Protection Agency. Acute Exposure Guidelines (AEGLs). http // www.epa.gov/oppt/aegl/sitemap.htm. October 3,2005. 

Bruckner, J.V., Keys, D.A., Fisher, J.W. (2004). The acute exposure guideline (AEGL) program applications of physiologically based pharmacokinetic modeling. J. Toxicol. Environ. Health. Part A 67 621-34. 

In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology the Subcommittee on Acute Exposure Guideline Levels, which prepared this report. This report is the first volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals. It reviews the appropriateness of the AEGLs for four chemicals for their scientific validity, completeness, and consistency with the NRC guideline reports. 

Exposure-response data from animal studies were used to derive acute exposure guideline level (AEGL) values for arsine. AEGL values derived with animal data which had complete exposure data were more scientifically valid than AEGLs estimated from limited anecdotal human data. The greater conser... 

AEGL Acute Exposure Guideline Levels describe the risk from single, nonrepetit-ive exposures to airborne chemicals in a once-in-a-lifetime event. They represent... 

This report is the second volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals. AEGL reports for aniline, arsine, monomethylhydrazine, and dimethylhydrazine were reviewed in the first volume. AEGL documents for five chemicals—phosgene, propylene glycol dinitrate, 1,1,1,2-tetrafluoroethane, 1,1-dichloro-l-fluoroethane, and hydrogen cyanide—are published as an appendix to this report. The subcommittee... 

Abbreviations ACGIH, American Conference of Governmental Industrial Hygienists AEGL, acute exposure guideline level AIHA, American Industrial Hygiene Association ... 

AEGLs Acute exposure guideline levels Aerobic Requiring oxygen... 

Watson, A., Opresko, D., Young, R., Hauschild, V. (2006a). Development and application of acute exposure guideline levels (AEGLs) for chemical warfare nerve and sulfur mustard agents. J. Toxicol. Environ. Health, Part B. 9 173-263. 

Acute Exposure Guideline Levels (AEGLs) for sulfur mustard have been developed for emergeney planning and... 

The US Army has developed HBESLs for lewisite (USACHPPM, 1999). Additionally, a chronic oral reference dose (RfD) is available (NRC, 1999 USACHPPM, 1999), as are inhalation and dermal RfDs (USACHPPM, 1999). Interim Acute Exposure Guidelines values (AEGLs) have been developed for lewisite. 

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