Aeromonas salmonicida

Studies on S-layers present on the cell envelopes of a great variety of pathogenic organisms [100] revealed that these crystalhne arrays can represent important virulence factors. Most detailed studies have been performed on the fish pathogenic bacteria Aeromonas salmonicida and Aeromonas hydrophila [102] and the human pathogen Campylobacter fetus uh p. fetus [103] and Bacillus anthracis [104]. For example, whole-cell preparations or partially purified cell products are currently used as attenuated vaccines against various fish pathogens [102,105]. 

Langefors, A., Lohm, J., Grahn, M., Andersen, O. and von Schantz, T. (2001) Association between major histocompatibility complex class IIB alleles and resistance to Aeromonas salmonicida in Atlantic salmon. Proc. R. Soc. B 268, 479-485. 

H 0 A-butanoyl-L-homoserine lactone, BHL or C4-HSL Aeromomas hydrophila Aeromonas salmonicida Pseudomonas aeruginosa, Serratia liquefaciens Extracellular protease, biofilm formation. Extracellular protease. Virulence factors - alkaline protease, cyanide, elastase, haemolysin, lectins, pyocyanin, rhaminolipid, RpoS Swarming, protease. 

Method Development and Application to the Analysis of the O-Chain Polysaccharide of Aeromonas salmonicida... 

Scheme 1 Structure of the O-PS from Aeromonas salmonicida strain A449.

Figure 2 CE-MS analysis of the O-PS (1.0 pg pF1) from Aeromonas salmonicida A449. (a) TIE (positive ion mode, m/z 100-1500) and extracted spectrum at 2.4 min, orifice voltage +30 V (b)TIE (negative ion mode, m/z 100-1500) and extracted spectrum at 2.2 min, orifice voltage -30 V (c) TIE (negative ion mode, m/z 100-1500) and extracted spectrum at 2.2 min, orifice voltage -200 V (d) TIE (positive ion mode, m/z 100-1500) and extracted spectrum at 2.4 min, orifice voltage +200 V. Reproduced from J. Li Z. Wang E. Altman, Rapid Commun. Mass Spectrom. 2005, 19,1305. Crown in the right of Canada.

Carbohydrate Analysis and Serological Classification of Typical and Atypical Isolates of Aeromonas salmonicida A Rationale for the Lipopolysaccharide-Based Classification of A. salmonicida... 

Table 1 Strains of Aeromonas salmonicida examined and their O-chain polysaccharide structural type...

Scheme 2 Structural variants of the O-chain polysaccharide of Aeromonas salmonicida LPS (a) type A, representative strain A449 (b) type B, representative strain 33659 (c) type C, representative strain N4705. Reproduced from Z. Wang X. Liu A. Dacanay B. A. Harrison M. Fast D. J. Colquhoun V. Lund L. L. Brown J. Li E. Altman, Fish Shellfish Immunol. 2007,23, 1095. Elsevier Ltd.

Figure 4 CE-MS and CE-MS/MS analysis (+ion mode) of LPS from in vivo Aeromonas salmonicida strain 80204-1 cells. Extracted mass spectrum and extracted MS/MS spectrum of precursor ion m/z 662.3 promoted using an orifice voltage of 120V. Reproduced from Z. Wang S. Larocque E. Vinogradov J.-R. Brisson A. Dacanay M. Greenwell L. L. Brown J. Li E. Altman, Eur. J. Biochem. 2004, 271, 4507. Blackwell Publishing Ltd.

Lissoclinotoxins A and B were active against ichthyopathogenic strains of Aeromonas salmonicida and Vibrio anguillarum, while lissoclinotoxin A also exhibited activity against resistant malaria, Plasmodium faciparum with an IC50 of 296 nM/L [21]. 

Wang, Z. et al. Struetural and serological characterization of the O-chain polysaccharide of Aeromonas salmonicida strains A449, 80204 and 80204-1. Carbohydr Res, 340, 693, 2005. 

It remains unexplained why the teleost Atlantic cod (Gadus morhua) failed to acquire MHC class II system with its invariant chain, and reactive CD4 T cells. Was it never acquired in the cod lineage, or was it lost to deletion, or is the cod operating an unusually effective innate immune system Indeed, it appears fliat the cod expanded its entire innate and the MHC class 1 adaptive immune system. There is adequate response to endotoxin, and to bacterial (Aeromonas salmonicida Vibrio anguillarum) and viral (pancreas necrosis virus) pathogens [987-989]. 

Against this background, interest was developed in the Gram-positive, high alpha-toxin-secreting Staphylococcus aureus (Wood 46) and the Gramnegative, protease-secreting Aeromonas salmonicida (Unilever 2864) both of... 

Staphylococcus aureus (Wood 46) (NCTC 7121) and Aeromonas salmonicida (Unilever 2864) were used. 

The fish pathogen Aeromonas salmonicida is the agent of a septicaemic disease of fish, primarily salmon 2md trout, termed furunculosis. Strains isolated from the infection are autoaggregating and have been shown to possess an additional protein layer known as the A layer or A protein. This... 

Figure 5.11 A Layer of Aeromonas salmonicida Separated from the Bacterial Cell. Note regularly ordered structure. Reproduced by permission Kay, W.W., Buckley, J.T., Ishiguru, E.E., Phipps, B.M., Monette, J.P.L. and Trust, T.J. (1981) J. BacterioL, 147,1077.

Bonet R, Simon-Pujol MD, Congregado F (1993) Effects of nutrients on exopolysaccharide production and surface properties of Aeromonas salmonicida. Appl Environ Microbiol 59 2437—2441 Booth GH, Tiller AK (1960) Polarization studies of mild steel in cultures of sulphate-redudng bacteria. Trans Faraday Soc 56 1689-1696 Booth GH, Tiller AK (1962) Polarization studies of mild steel in cultures of sulphate-redudng bacteria. Part 2 thermophilic organisms. Trans Faraday Soc 58 110-115... 

Vibriosis (Listonella (Vibrio) anguillaruni) Furunculosis (Aeromonas salmonicida)... 

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