Advanced wound dressings

There is a very high market potential for advanced wound dressings. The wound care industry generated between US 3.5 and 4.5 billion in 2003-6, mostly from the US and Europe. The global advanced wound care market is the fastest growing area and it is estimated that it will be worth US 16.3 billion in 2018. ... 

Y Qin, O C Ag xir, X Wang and D K Gilding, Novel polysaccharide fibres for advanced wound dressings . In S.C. Anandfed.) Medical Textiles 96, Woodhead publishing, Cambridge, 15-20,(1997). 

Our main interest in this field was the evaluation of materials performance after different exposure times in simulated physiological environments. As a consequence of the products we develop (mostly materials for use in preparation of advanced wound dressings), we tried to simplify the testing environments to simple physico-chemical... 

Qin, Y. (2001). Advanced wound dressings. Journal of Textile Institute, 92. 

Czajka R. Development of medical textile market. Fibres Text East Eur 2005 13( 1) 13-5. Qin Y. Advanced wound dressings. J Text Inst 2001 92(2) 127-38. 

Qin Y. Review on advanced wound dressings. J Text Inst 2001 92 127-38. 

In order to provide the best solutions for wound-care practitioners, new types of advanced wound dressings and wound-management materials are being developed to provide the means of ensuring the best possible patient outcome. The aims of the new developments can be summarized into the following three areas. 

Silver has broad-spectrum antimicrobial properties and a low level of toxicity to the human body. In recent years, as bacterial resistance to antibiotics became common and more and more attention was paid to cross-infection in hospital wards, wound dressings with antimicrobial properties became increasingly popular. Silver is gaining in importance as an effective antimicrobial component in advanced wound dressings. 

It is the aim of this contribution to present advances in research, development, and application in the field of nanocelluloses. The topics combine selected results on nanocellulosics from bacteria and wood as well as their use as technical membranes and composites with the first long-time study of cellulose in the animal body for the development of medical devices such as artificial blood vessels, and the application of bacterial nanocellulose as animal wound dressings and cosmetic tissues. Therefore, the review has brought together colleagues from chemistry, medicine, and biotechnology. 

Advanced wound management products containing silver have been developed to treat difficult-to-heal wounds, chronic ulcers, and extensive burns. Odor absorbing dressings adsorb polarized bacteria onto the surface of the charcoal cloth used in the formulation. The silver present in the dressing exerts a bactericidal effect that gradually diminishes as wound exudate saturates the material. 

The modification of polymers and fibrous surfaces to alter the porosity, wettability and other characteristics of polymeric substrates, will enable the prodnction of implants and biomedical devices which exhibit greater resistance to microbial adhesion and biofilm formation. A nnmber of polymers have been developed that can be incorporated into cellulose and other materials, which will provide significant advances in many fields snch as food packaging, textiles, wound dressings, coating of catheter tnbes and sterile surfaces. 

Textile materials can be used in moist wound management as fibres themselves (advanced fibres such as alginate and chitosan fibres), or conventional/advanced fibres can be modified or coated with various substances such as honey or hydrogels to obtain special properties such as ultra-absorbency, drag release, etc. In general, textiles used in wound-dressing products come in all possible forms, including fibres, nanofibres, filaments, yarns, and woven/knitted/non-woven and composite materials. 

Zahedi, P., Rezaeian, I., Ranaei-Siadat, S.O., Jafari, S.H., Supaphol, P., 2010. A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polymers for Advanced Technologies 21 (2), 77—95. 

L.I.F. Moura, A.M.A. Dias, E. Carvalhoa, H.C. de Sousa, Recent advances on the development of wound dressings for diabetic foot ulcer treatment—a review, Biomaterialia 9 (2013) 7093-7114. 

M Miraftab, Q Qiao, J F Kennedy, S C Anand and G Collyer, Advanced materials for wound dressings biofimctional mixed carbohydrate polymers. In Medical Textiles, S C Anand (ed.), Woodhead Publishing Ltd, Cambridge, UK, 2001, 164-172. 

Recent advances in the field of biomaterials and their medical applications indicate the significance and potential of various nanoceUulose in the development of novel classes of medical devices and applications in healthcare and veterinary medicine. The physical and mechanical properties of nanocellulose are attributes that enable nanocellulose membranes to function as effective temporary wound dressings. On the other hand, because implantable biomaterials (i.e., scaffolds) are also needed, a new approach has been undertaken to apply cellulose as a material entirely integrated into the body, either as a bone or skin graft. 

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