Acid-fast bacilli

CSF stain Negative Positive Gram stain (60%-90%) Negative Positive India ink stain (Cryptococcus) Positive acid-fast bacilli stain... 

The lipid constituents of the acid-fast bacilli, particularly the tubercle bacillus, have been extensively studied and there is good evidence that carbohydrate-lipid complexes play an important part in the sero-... 

Patients who still have acid-fast bacilli-positive sputum smears after 2 months of therapy... 

Symptomatic patients should be isolated and have sputum samples sent for acid-fast bacilli stains every 1 to 2 weeks until two consecutive smears are... 

In an extensive study undertaken in Nigeria of several patients suffering from pulmonary tuberculosis diagnosed by means of the radiological features of tuberculous bronchopneumonia on chest X-ray and detection of acid-fast bacilli in the patients sputum by simple microscopy, serum immunoglobulin measurements were made (M27). The wide age distribution of the patients and controls are summarized in Table 12, and the immunoglobulin concentration results in Tables 13 and 14. The tuber-... 

Acid-fast bacteria, acid-fast bacilli and as rickettsia stain/Cain s method for mitochondria NEtj For staining Negri bodies in nerve cells... 

A 39-year-old man has AIDS and a CD4 count less than 50. Recently he has had chills and fever. Several blood cultures drawn especially for acid-fast bacilli are positive. Which antibiotic should be included in a treatment regimen for this disease ... 

Acid-fast bacilli Rod-shaped retains color of certain stains even when treated with acid Mycobacterium leprae, Mycobacterium tuberculosis... 

Negative means no acid-fast bacilli detected in the 20-22 microscopic fields in any of the smears. 

JS, a 46-year-old male patient, returned from India with cough, malaise, weight loss and night sweats. Sputum culture showed acid-fast bacilli and 3 days later Mycobacterium tuberculosis was isolated. 

Comprehensive reviews of the earlier investigations have been published by Cornet and by Wells, Dewitt and Long. A recent review of the composition of tuberculin and the proteins of acid-fast bacilli has been published by Seibert. Andersonhas summarized the chemical knowledge of the lipids of M. tuberculosis. 

Anderson found that a substance of lipid nature was associated with the skeletal material of acid-fast bacilli. This lipid was not removed by neutral organic solvents but could be extracted with an ethereal or chloroform solution of hydrogen chloride. Saponification of these firmly-bound lipids yielded a polysaccharide having properties similar to those of the polysaccharide obtained from the purified wax. Phthiocerol was not detected. The polysaccharide was shown to contain... 

Acid-fast bacilli Mycobaazerium tubercu/osis isoniazid + rifampicin pyrazinamidc a quinolone or cycloserine or capreomycm or... 

The autopsy confirmed the diagnoses and showed acid-fast bacilli in the adventitia of the basilar artery the paralysis of the oculomotor nerve was caused by the brain lesion. Defective function of macrophages was suggested as the possible cause of the underlying immunological abnormality (81). 

Bayers, B.R., 1974. Iron transport in gram positive and acid fast bacilli. In J.B. Neilands (Editor), Microbial Iron Metabolism. Academic, New York, NY, pp. 83—105. 

The standard methods for detection of MTb include acid-fast bacilli (AFB) smear and conventional and liquid culture methods. The AFB smear is rapid, but has a poor sensitivity of 20% to 80%. Another challenge with the AFB smear is that it cannot distinguish MTb from nontuberculous mycobacteria (NTM), such as M. avium-complex (MAC). This distinction is important because disseminated MAC and MTb are both common infections in persons with AIDS. Culture methods for the detection of MTb are sensitive, but growth detectable by standard methods may require 6 to 8 weeks in a culture. Growth often occurs more quickly in liquid culture than with conventional methods, but can still require weeks. With these limitations of culture methods, there was great enthusiasm for nucleic acid testing as a rapid, sensitive method for detection of MTb, especially given the needs to rapidly isolate patients with active, untreated disease and to initiate prompt therapy, particularly in immunocompromised hosts. 

Micro caseating granulomas with acid-fast bacilli Lab positive skin test (PPD)... 

Acid-fast bacilli Culture and sensitivity Cytology... 

On saponification mycobactin splits Into mycobactic acid and cobactin. Synthetic studies Black et at., /lust J, Chem. 25t 2155 (1972). Synthesis of mycobactin S2 p. J. Maurer, M. J, Miller, /. Am. Chem. Soc. 105, 240 (1983). Review of early studies Rose, Snow, Mycobactin A Growth Factor for Acid-Fast Bacilli in G. E. W, Wol-stenholme, M, P. Cameron, C. M. O Connor, Ciba Foundation Symposium on Expti. Tuberculosis Bacillus and Host 1955, 41-54. Comprehensive review Snow Bacterial. Rev, 34, 99 (1970). 

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