A V-dimethylacrylamide

One of the potential applications of these ABC triblock copolymers was explored by Hillmyer and coworkers in 2005 [118]. They have prepared nanoporous membranes of polystyrene with controlled pore wall functionality from the selective degradation of ordered ABC triblock copolymers. By using a combination of controlled ring-opening and free-radical polymerizations, a triblock copolymer polylactide-/j-poly(A,/V-dimethylacrylamide)-ib-polystyrene (PLA-h-PDMA-h-PS) has been prepared. Following the self-assembly in bulk, cylinders of PLA are dispersed into a matrix of PS and the central PDMA block localized at the PS-PLA interface. After a selective etching of the PLA cylinders, a nanoporous PS monolith is formed with pore walls coated with hydrophilic PDMA. 

LIU Liu, S.Q., Tong, Y.W., and Yang, Y.-Y., Incorporation and in vitro release of doxombicin in thermally sensitive micelles made from poly(iV-isopropylacrylamide-co-A/ V-dimethylacrylamide)-6-poly(D,L-lactide-co-glycolide) with varying compositions, Biomaterials, 26, 5064, 2005. 

DMAM, A/,/V-dimethylacrylamide EA, ethyl acrylate NIPAM, /V-isopropyl acrylamide IBA, fezFbutyl acryiate. 

The cycloaddition to /V,/V-dimethylacrylamide could also be catalyzed by monoclonal antibodies. The cycloadducts were isolated with excellent selectivity (er 99 1) (193). Unfortunately, a definitive explanation both for the high regio- and stereochemical outcome of this reaction is lacking, and the preparative assets of this approach remain to be seen. 

Polyethylene has been grafted with acrylic acid, 2-hydroxyethyl methacrylate//V,/V-dimethylacrylamide, or methacrylic acid//V,/V-dimethylacrylamide to yield supports (e.g. Figure 2.10) suitable for the synthesis of peptides [2,222-224] and other compounds [216,225,226]. A similar support, also suitable for the synthesis of peptides, is polypropylene grafted with hydroxypropyl acrylate [227]. These supports can be used as membranes or as crown-shaped pinheads (Multipin 2-4 mm diameter) with loadings of 1.2-2.2 pmol per crown. 

Ammonium persulfate A -Hexadecyl methacrylate Stearyl methacrylate A-Octadecyl acrylate 77-Octadecyl methacrylate Dococyl acrylate Initial monomer concentration Cetyltrimethylammonium bromide Cooperative diffusion coefficient Apparent diffusion coefficient Dynamic light scattering iV V-Dimethylacrylamide Dimethyl sulfoxide Tensile modulus... 

References cited provide details of polymerization of the monomers indicated. Heterogeneous polymerizations (emulsion, miniemulsion) are indicated by the monomer being in italics. Monomer/RAF agent combinations that are relatively ineffective are indicated by the monomer being in parentheses. DMAM, A/,W-dimethylacrylamide EHA, 2-ethylhexyl acrylate HPMAM, /V-(2-hydroxypropyl) methacrylamide MAM, methacrylamide NIPAM, W-isopropyl acrylamide tBA, ferf-butyl acrylate VBz, vinyl benzoate. 

As an illustrative example, the monomers used for the preparation of a typical polyacrylamide support (Pepsyn) and its schematic representation are sketched in Figure 2.6. The ester functionality, obtained by copolymerization with A-acryloylsarco-sine methyl ester, can be used as the attachment point for a suitable linker. This can be achieved by aminolysis with ethylenediamine, followed by acylation of the resulting primary amine with 3-(4-hydroxymethyl)phenylpropionic acid [163] or other linkers. Similar supports have been prepared by copolymerization of protected allylamine [37] or lV-(acryloyl)-l,3-diaminopropane [173] with V,lV-dimethylacrylamide and... 

In an interesting insertion reaction, [RuHCl(CO)(PPh3)3] and RCH—CHR dimethyl fumarate, methyl sorbate, methyl acrylate, V,A -dimethylacrylamide or CH2=CH-2-py) give... 

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