Wound healing, moist

Chvapil et al. investigated the effects of epidermal growth factor (EGF) in a lanolin vehicle on partial thickness wounds 49 A beneficial effect of lanolin vehicle was observed with little additional benefit from EGF. Lanolin statistically increased the rate of reepithelialization, the thickness of the dermis, and the number of cells in the dermis. Lanolin is likely to promote wound healing by maintaining a moist environment.50,51... 

The first clinical use of penicillin in the United States occurred with the survivors of the Coconut Grove fire in 1942. Bum victims are notoriously prone to severe Staphylococcus aureus infections, and before the early sulfa drugs and penicillin, allopathic physicians knew little about how to prevent them. Aloe and honey are perhaps the two most powerful substances that can be applied externally to speed wound healing and prevent infections in burn victims. One especially important attribute possessed by both substances is that they are liquid. They keep bum tissue moist, soothe the damaged tissues, and restore lost body fluids (a problem for bum victims) directly through the skin. At the same time they are potent anti-inflammatories and antibacterials. It is nearly impossible for a staph infection to get started when either substance is used on burned skin. Clinical practitioners who regularly use aloe report excellent results when it is used on skin wounds of any degree of severity and from any source. 

Overview, 2015. Overview of Wound Healing in a Moist Environment http //www.wound-treatment.jp/english/index-e.htm (viewed 2.2.2015.). 

GeUing facilitates non-adherence to the wound, which permits non-traumatic dressing removal. Gelling also maintains moist environment at the wound site that promotes wound healing. 

Atiyeh, B.S., Ioannovich, J., Al-Amm, C.A., El-Musa, K.A., 2002. Management of acute and chronic open wounds the importance of moist environment in optimal wound healing. Curr. Pharm. Biotechnol. 3, 179-195. 

Alginate hydrogel Brown seaweed Moist microenvironment maintained Bacterial infection minimized Wound healing facilitated Useful for growth factor delivery Useful as graft in deepthickness wounds Fibroblast proliferation stimulated D Ayala et al. (2008) and Balakrishnan et al. (2006)... 

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