Weight gain drug-induced

Of particular importance in the genatnc patient Hypoglycemia, weight gain, drug-induced disulfiram-like reaction... 

Baptista T. Body weight gain induced by antipsychotic drugs mechanisms and management. Acta Psychiatr Scand 1999 100(1) 3—16... 

Kim, S.F., Huang, A.S., Snowman, A.M., Teuscher, C. and Snyder, S.H. (2007) From the coven Antipsychotic drug-induced weight gain mediated by histamine HI receptor-linked activation of hypothalamic AMP-kinase. Proceedings of the National Academy of Sciences of the United States of America, 104 (9), 3456-3459. 

Overall, bupropion has a favorable side-effect profile. The drug is associated with little or no weight gain, has few effects on cardiac conduction, and has minimal sexual side effects. Disadvantages include an increased risk of medication-induced seizures at higher-than-recommended doses. 

Imipramine Mixed and variable blockade of NET and SERT Like SNRIs plus significant blockade of autonomic nervous system and histamine receptors Major depression not responsive to other drugs chronic pain disorders incontinence obsessive-compulsive disorder (clomipramine) Long half-lives CYP substrates active metabolites Toxicity Anticholinergic, G.-blocking effects, sedation, weight gain, arrhythmias, and seizures in overdose Interactions CYP inducers and inhibitors... 

Sengupta SM, Klink R, Stip E, Baptista T, Malla A, Joober R. Weight gain and hpid metabohc abnormalities induced by olanzapine in first-episode, drug-naive patients with psychotic disorders. Schizophr Res 2005 80 131-3. 

Side effects. The common dose-related side effects of valproate include nausea, vomiting and gastrointestinal distress weight gain is frequent (estimated as high as 30%) and may be associated with a drug-induced decrease in the beta oxidation of fatty acids. Sedation is also frequent. Alopecia is an unusual side effect of valproate, possibly caused by an abnormal metabolite. Valproate has a number of metabolically linked side... 

Mechanistic Connections Between Glucose/ Lipid Disturbances and Weight Gain Induced by Antipsychotic Drugs... 

---