Vessels ventilation system

ACT introduced the 357 Flexible Biomolecular Synthesizer in 1993.The Model 357 FBS is also a two arm robotic system, with a reaction block that incorporates thirty six 9.0-mL reaction wells and a single 600-mL well. The larger vessel permits the spht and mix technique for the generation of peptide combinatorial libraries.The scale range is 5 to 250 pmol and 9 mmol for the 9.0-mL and 600-mL reactor, respectively. The Model 357 FBS also has a variable speed orbital nnixer, nitrogen assisted bottom filtration and a built-in ventilation system. 

Figure 2 Typical specific ventilation system designed to protect operators during the care of vessels with cytotopic-high potency compounds.

Wet Scrubber Cell. The wet scrubber forms the second part of the secondary off-gas treatment. It removes active volatile contaminants from the off-gas stream, together with some of the remaining particulates before filtration. The wet scrubber operates continuously. Filter Cell. The filter cell contains banks of HEPA filters, associated ductwork, and ancillary equipment. The function of the filter cell is to filter the off-gas from the vessel and cell ventilation systems before the off-gas is discharged to the environment. 

The situation is similar for the melter. The melter would contain over 100 kg of Pu and is not designed for inherent criticality safety with that mass amount. Also, the ventilation system was not designed for the possibility of Pu offgassing. Major redesign of the DWPF vessels and ventilation system would be required. 

If parts are critical, additional test certificates will be claimed from the suppliers. All gaskets and piping parts have to fulfil the requirements of the pressure vessels guideline (Druckbehalter VO 97 3/EC). An independent ventilation system paired with leak detection will guarantee that no explosive gas mixes can appear at any time during operation. 

Having defined the hazardous areas it may be possible to reduce their extent. For instance, a ventilation system can be used to pull air into the vessel through the chargehole, and this will reduce the size of, or eliminate, the hazardous area outside the vessel a sealed system can also be used (whenever possible a sealed system using a mechanical device for the remote charging of the powder is always to be preferred over manual addition through a chargehole). It is unlikely that ventilation can be used to avoid a flammable atmosphere inside the vessel as the air flow necessary would evaporate too much solvent. 

Reduced fluence of the reactor vessel, absence of primary circiut pipeimes, absence of links with ventilation systems m the other rooms R,S... 

If there is a loss of containment event, the BSD should isolate all vessels so that the maximum leak is limited to what is in a vessel or piping system. It is particularly important that all risers are blocked in and vessels under pressure are blown down to the flare. All ventilation systems should be started and the fire main brought up to operating pressure. 

To withstand large SG leaks (a postulated rupture of several SG tubes, i.e., a beyond design basis initiating event), the gas system is connected with the passive heat removal system (PHRS) tank. The connection line is blocked by a membrane device designed for rupture under a gas system pressure of 1 MPa that is not dangerous for the reactor mono-block vessel. In the event of membrane rupture, the steam will be condensed in the water of the PHRS tank. In this, the volatile radionuclides of the cover gas remain in the tank water and the radioactive uncondensed gases will be released into the atmosphere via the filtered ventilation system. The radioactivity release will not exceed the permissible levels. 

The reactor pressure vessel and containment have been isolated from the rest of the primary circuit and a ventilation system installed into the reactor vault and pressure vessel... 

It is very simple to perform batch fermentation in a small flask with a volume of say 200 ml. Now our target is to use a 2 litre B. Braun fermenter. All accessories are shown in Figure 10.5. The fermentation vessel only, as shown in Figure 10.6, with about 250 ml of media without any accessories but with some silicon tubing attached with a filter for ventilation is autoclaved at a 131 °C for 10 minutes at 15psig.9 After that, the system is handled with special care and all accessories attached. Media is separately sterilised and pumped into the vessel. Inoculum is transferred and the batch experiment is started right after the inoculation of seed culture. An initial sample is withdrawn for analysis. 

The section (S) used in this expression is the narrowest part of the piping system, for example, the gas ventilation. The gas release across the liquid surface in a vessel may lead to swelling. This effect may also be assessed using the section of the vessel. The capacity of a scrubber may also be used as an assessment criterion. 

---