Vecuronium bromide

C2H3CIO 75-36-5) see Acebutolol Acetiamine Acetylcholine chloride L-Alanine Benfurodil hemisuccinate . Chlorprothixene Flumetasone Ibuprofen lotalamic acid loxitalamic acid Levodopa Methestrol dipropionate Midecamycin acetate Naproxen Nimesulide Paclitaxel Paramethasone Phensuximide Retinol Rocuronium bromide Rofecoxib Ropinirole Tazarotene Thiopropazate Tiracizine Vecuronium bromide... 

C32H37NO4 76811-98-8) see Fexofenadine hydrochloride 4-[4-[4-(hydroxydiphenylmethyl)-l-piperidinyl]-l-oxo-butyl]-a,a-dimcthylbenzeneacetic acid ethyl ester (C34H4[N04 76812-02-7) see Fexofenadine hydrochloride 3a-hydroxy-2p,16p-dipiperidino-5a-androstan-17-one (C2cjH4jN202 13522-14-0) see Pancuronium bromide Vecuronium bromide 9-hydroxyellipticine... 

CjHgOj 108-22-5) see Desoxycortone acetate Estriol Pancuronium bromide Pipecuronium bromide Vecuronium bromide... 

The stability of moisture-sensitive drugs has been studied by Vromans and Schalks [1.143] using amorphous vecuronium bromide. Its decomposition in a formulation depends more on the water activity aw (see Chapter 4, point 2) than on the water content. Glass-forming excipients may not only be cryoprotective but also stabilizing. 

Vecuronium bromide (Norcuron) is chemically identical to pancuronium except for a tertiary amine in place of a quaternary nitrogen. However, some of the drug will exist as the bisquatemary compound, depending on body pH. Vecuronium has a moderate onset of action (2.4 minutes) and a duration of effect of about 50 minutes. Like pancuronium, it does not block ganglia or vagal neuroeffector junctions, does not release histamine, and is eliminated by urinary excretion. 

Frusemide is physically incompatible with diltiazem hydrochloride, dobutamine hydrochloride, dopamine hydrochloride, labetalol hydrochloride, midazolam hydrochloride, milrinone lactate, nicardipine hydrochloride, parenteral nutrient solutions, cisatracurium besylate, and vecuronium bromide. 

C.2H27N04 107188-37-4) see Troglitazone 17-acetoxy-5a-androsta-2,16-diene (C2 Hw()2 50588-42-6) see Pancuronium bromide Pipecuronium bromide Vecuronium bromide... 

Ulsamer B. Vecuroniumbromid Beeinflussung der Pharmakodynamik durch Etomidat, Cimetidin und Ranitidin. [Vecuronium bromide modification of its pharmacodynamics by etomidate, cimetidine and ranitidine.] Anaesthesist 1988 37(8) 504-9. 

The neuromuscular blocking effects of vecuronium bromide can be enhanced by inhalation anesthetics. 

Symptoms suggestive of severe sensorimotor neuropathy developed in a 40-year-old woman 15 days after admission for a severe exacerbation of asthma (7). During this time she was given isoflurane 0.5-3% in oxygen, vecuronium bromide 4-6 mg/hour, and fentanyl 100 micrograms/hour. The neuropathy resolved spontaneously over the next 3 months. 

Rashkovsky OM, Agoston S, Ket JM. Interaction between pancuronium bromide and vecuronium bromide. Br J Anaesth I985 57(II) I063-6. 

Spence AG, Barnetson RS. Reaction to vecuronium bromide. Lancet 1985 l(8435) 979-80. 

Lienhart A, Desnault H, Guggiari M, et al. Vecuronium bromide dose response curve and haemodynamic effects in anaesthetized man. In Agoston S, editor. Clinical Experiences with Norcuron. Amsterdam Excerpta Medica, 1982 46. 

Bencini AF, Scaf AH, Sohn YJ, Meistelman C, Lienhart A, Kersten UW, Schwarz S, Agoston S. Disposition and urinary excretion of vecuronium bromide in anesthetized patients with normal renal function or renal failure. Anesth Analg 1986 65(3) 245-51. 

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