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Vaginal candidiasis, treatment

Thrombolytic agents a need for improvement Thyroid preparations Trace minerals essential for health Traveler s diarrhea prevention of Tuberculosis treatment of Upper respiratory tract infection treatment of Urinary tract infections treatment of Uveitis management of Vaginal candidiasis treatment of Vasodilators effects on cardiac output (CO)... [Pg.808]

Daneshmend [104] measured the serum concentration of miconazole in 11 healthy adult females for 72 h following a single 1200 mg vaginal pessary. The mean peak serum miconazole concentration was 10.4 pg/L and the mean elimination half-life was 56.8 h. The mean area under the serum concentration-time curve was 967 pg/L/h. The calculated mean systemic bioavailability of the vaginal pessary was 1.4%. There was large intersubject variation in serum miconazole pharmacokinetics. This formulation may provide effective single dose treatment for vaginal candidiasis. [Pg.58]

Use primarily for treatment of patients with progressive and potentially fatal fungal infections. Do not use to treat noninvasive forms of fungal disease such as oral thrush, vaginal candidiasis, and esophageal candidiasis in patients with normal neutrophil counts. [Pg.1663]

Fluconazole is very effective in the treatment of infections with most Candida spp. Thrush in the end-stage AIDS patient, often refractory to nystatin, clotrimazole, and ketoconazole, can usually be suppressed with oral fluconazole. AIDS patients with esophageal candidiasis also usually respond to fluconazole. A single 150-mg dose has been shown to be effective treatment for vaginal candidiasis. A 3-day course of oral fluconazole is effective treatment for Candida urinary tract infection and is more convenient than amphotericin B bladder irrigation. Preliminary findings suggest that Candida endophthalmitis can be successfully treated with fluconazole. Stable nonneutropenic patients with candidemia can be adequately treated with fluconazole, but unstable, immunosuppressed patients should initially receive... [Pg.598]

Despite negligible cerebrospinal fluid concentrations, itraconazole shows promise in the treatment of cryptococcal and coccidioidal meningitis. Additional uses for itraconazole include treatment of vaginal candidiasis, tinea versicolor, dermatophyte infections, and onychomycosis. Fungal naU infections account for most use of this drug in the outpatient setting. [Pg.599]

Cyclopirox olamine is used in the treatment of tinea infections, dermal and vaginal candidiasis. [Pg.347]

Since oral contraceptive users sometimes need to be treated for vaginal candidiasis, the question arises which of the available treatments can be used without risk of impairing contraception. In a crossover placebo-con-trolled study, fluconazole 300 mg weekly for two cycles has been studied in 21 healthy women using Ortho-Novum 7/7/7 as a contraceptive (344). Fluconazole in this dose, which is twice that ordinarily recommended, produced small but statistically significant increases in the AUCo-24 for both ethinylestradiol (mean 24% increase) and norethindrone (mean 13%). The Cmax of ethinylestradiol was slightly, but just significantly, higher... [Pg.240]

Stein, G.E., and N. Mummaw. 1993. Placebo-controlled trial of itraconazole for treatment of acute vaginal candidiasis. Antimicrob Agents Chemother 37 89. [Pg.433]

Gouveia DC, Jones da SUva C. Oxiconazole in the treatment of vaginal candidiasis single dose versus 3-day treatment with econazole. Pharmatherapeutica 1984 3(10) 682-5. [Pg.304]

B. Azole antifungals include systemic agents such as keto-conazole, fluconazole, itraconazole, and voriconazole. Topical agents used for the treatment of vaginal candidiasis and thrush include miconazole and clotrimazole. The pharmacologic properties of the systemic azoles differ considerably. Ketoconazole, the first oral azole developed, has poor bioavailability and requires an acidic environment for enhanced absorption. Thus, initial studies required ketoconazole to be administered with a cola to increase bioavailability. Fluconazole, unlike itraconazole and ketoconazole, is hydrophillic and has increased penetration across the blood-brain barrier. Fluconazole is also the only azole that is renally eliminated. [Pg.130]

Miconazole nitrute is supplied in a variety of dosage fonns (cream, lotion, powder, and spray) for the treatment of tinea infections and cuiiineous candidiasis. Vaginal creams and. suppositories are also available for the treatment of vaginal candidiasis. A conceiiiraiion of 2% of the salt is u.sed in moii topical preparations. [Pg.242]

The first stage in practicing EBM is to define the precise question to which an evidence-based answer is required. A carefully focused question will inform the search for relevant evidence, and should (hopefully) avoid excessive retrieval of irrelevant publications and other information sources. For example, a clinician who wishes to know whether it is best to use oral or topical antifungals for the treatment of vaginal candidiasis could articulate the question as What is the relative effectiveness of oral versus intra-vaginal antifungals for the treatment of uncomplicated vulvovaginal candidiasis ... [Pg.348]

If vaginal candidiasis has not been previously diagnosed by a doctor. There are other vaginal infections, some serious and all requiring treatment with prescription-only medication, with symptoms that could be confused with thrush. An initial medical diagnosis of candidiasis is necessary so that sufferers can recognise the condition subsequently. [Pg.212]

First statement For systemic treatment of vaginal candidiasis in a patient with liver disease, itraconazole is preferable to fluconazole. [Pg.214]

Tooley PJ. Patient and doctor preferences in the treatment of vaginal candidiasis. Practitioner 1985 229 655-662. [Pg.2159]


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See also in sourсe #XX -- [ Pg.1353 ]




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