V genes rearrangement

Roes, J., Hiippi, K., Rajewsky, K., Sablitzky, F. (1989). V gene rearrangement is required to fully activate the hypermutation mechanism in B cells. J. Immunol. 142,1022-1026. 

Gorski, J., Rollini, P., Mach, B. (1983). Somatic mutations of immunoglobulin variable genes are restricted to the rearranged V gene. Science 220, 1179-1181. 

Di Lorenzo, T. P., Graser, R. T., Ono, T., Christianson, G. J., Chapman, H. D., Roopenian, D. C., Nathenson, S. G. and Serreze, D. V. (1998). Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc. Natl. Acad. Sci. USA 95, 12538-12543. 

Bensimon, C., P. Chastagner, and M. Zouali. 1994. Human lupus anti-DNA autoantibodies undergo essentially primary V kappa gene rearrangements. The EMBO journal 13 2951-2962. 

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