Using Relatively Generic Information

Webster s definition for database is a large collection of data in a computer, organized so that it can be expanded, updated, and retrieved rapidly for various uses. An LC/MS database established for drug impurities contains multi-dimensional information such as relative retention times, UV spectra, molecular mass and substructural information. In order for the information to be updated and expanded, the methods used for information collection need to be unified. A generic LC/MS method allows relevant information to be collected in a consistent... 

This method can also provide important information on the degree of systemic exposure for the assessment of bioequivalence, by comparing the AUCoo for innovator and generic products, using the following equation for the relative systemic availability ... 

The compositions of titrated solutions and titrants used, as inferred from the very condensed information given in the paper, are summarised in Table A-25. In all systems, carbonate was always in large excess of Zr. From the relative offset of the titration curves, the authors determined the number of basic ligands (the sum of OH and CO3" groups) to be close to 4, yielding the generic formula Zr(0H)x(C03)y for the complex, with X 3- y = 4. Unfortunately, in the paper no details are given on these calculations, so that we were not able to reproduce them. 

The proliferation of information on the Internet can be overwhelming. It is important to know how to move around the Internet using search engines, generic sites, and links. The Internet can provide much useful information in a relatively short period of time. 

Once the need for a network has been determined, the locations of terminals, servers, and information storage equipment must be established. Local area networks (LANs) and the worldwide web (WWW, or Internet) can link access points located in adjacent rooms or halfway around the world. However, it is critical that the network uses consistent computer and data transmittal protocols in order to provide uninterrupted, information handling in an efficient manner. For example, serial communication via an RS-232 port is relatively common, but too slow for most machine applications. Ethernet communication via transmission control protocol/Internet protocol (TCP/IP) is a preferred method because most equipment suppliers offer this network option. The TCP/IP method allows computers to share resources, no matter whether the operating system is for an Apple , a version of the Microsoft operating system for PCs, or the UNIX operating system. Also, the Semiconductor Equipment Communication Standard (SECS)/Generic Equipment Model (GEM) is widely used as the interface between the host computer and assembly machines. 

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