Uric acid in serum

Pyrimidines and purines derivatives act as bases and can be acquired through the diet. In particular, organ meats such as liver are a rich source of DNA and RNA. Most dietary purines are oxidized by enzymes to uric acid in the intestinal mucosa that is their excretory product in humans. The desease known as gout is related to high levels of uric acid in serum and the result of deposition of urate salts in various tissues. [Pg.902]

Duncan P, Gochman N, Cooper T, Smith E, Bayse D (1980) Development and evaluation of a candidate reference method for uric acid in serum or plasma. CDC, Atlanta, Ga. [Pg.164]

Johnson WJ, Chartrand A (1978) Allantoxanamide a potent new uricase inhibitor in vivo. Life Sci 23 2239-2244 Kageyama N (1971) A direct colorimetric determination of uric acid in serum and urine with uricase-catalase system. Clin Chim Acta 31 421-426... [Pg.113]

Ingestion. High uric acid in serum and urine, loss of appetite, diarrhea, slow growth, anemia, gout-like lesions. Molybdenosis. [Pg.4809]

T12. Troy, R. J., and Purdy, W. C., The coulometric determination of uric acid in serum and urine. Clin. Chim. Acta 27, 401-408 (1970). [Pg.377]

Kock, R. Seitz, S. Delvoux, B. Greiling, H. A method for the simultaneous determination of creatinine and uric acid in serum by high-performance-liquid-chromatography evaluated versus reference methods. Eur. J. Clin. Chem. Clin. Biochem. 1995, 33, 23-29. [Pg.469]

Kock, R. Delvoux, B. Tilhnanns, U. Greihng, H. A candidate reference method for the determination of uric acid in serum based on high-performance hquid chromatography, compared with an isotope dilution-gas chromatography-mass spectrometer method. J. Chn. Chem. Clin. Biochem. 1989, 27, 157-162. [Pg.469]

R94 Cattozzo, G., Franzini, C., Hubbuch, A.D. and Tritschler, W. (1988). Evaluation of determination of uric acid in serum and whole blood with the Reflotron. Clin. Chem. 34, 414-416. [Pg.427]

Chang, E.S. (1979). A solid phase strip test for the determination of uric acid in serum. Clin. Chem. 25,1091. Abstr. 142. [Pg.534]

Fossati P, Prencipe L, Berti G. Use of 3,5-dichloro-2 hydroxybenzenesulfonic acid/4-amino-phenazone chromogenic system in direct enzymic assay of uric acid in serum and urine. Clin Chem 1980 26 227-31. [Pg.829]

Lamb EJ, Price CP. Use of azure-D2 for the measurement of uric acid in serum. Eur J Clin Chem Clin Biochem 1995 33 595-601. [Pg.830]

White RM, Cross RE, Savory J. Enzyme coupled measurement of uric acid in serum with a centrifugal analyser. Chn Chem 1977 23 1538-40. [Pg.834]

Normal levels of uric acid in serum are 200-400 pmol/1. Since uric acid is a risk factor for gout and other diseases, diagnosis of hyperuricemia is increasingly important. [Pg.306]

T2. Tabata, M., Fukunaga, C., Ohyabu, M., and Murachi, T., Highly sensitive flow injection analysis of glucose and uric acid in serum using an immobilized enzyme column and chemiluminescence. J. Appl. Biochem. 6, 251-258 (1984). [Pg.179]

M. Tabata, C. Fukunaga, M. Ohyabu, and T. Murachi, Highly Sensitive Flow Injection Analysis of Glucose and Uric Acid in Serum Using an Immobilized Enzyme Column and Chemiluminescence. J. Appl. Biochem., 6 (1984) 251. [Pg.427]

Increased uric acid in serum as a result of animal protein overconsumption and alcohol abuse is frequent nowadays. Concentrations above 6,5 mg uric acid/100 ml serum can lead to the deposition of uric acid or its salts in tissues, which in turn can lead to gout. Up to 40% of the patients suffering from gout also have uric acid nephrolithiasis. Without showing the symptoms of gout, however, uric acid stones as well as urate stones can form when the solubility product is exceeded either because of extreme uricosuria and/or because of an unfavorable urinary pH. About 20% of all urinary stones are totally or partially composed of uric acid or urate. [Pg.81]

Fig. 3 Uric acid in serum after the purine loading test [Fa. Dr. E. Fresenius KG, Oberursel/Taunus (Germany)].

Parallel to the increased uric acid in serum the urinary uric acid excretion remains elevated for several days in stone formers. [Pg.87]

Table 10 Percentage frequency of increased uric acid in serum and urine...

In humans, a high incidence of gout has been associated with abnormally high molybdenum concentrations in the soils and plants of Armenia [42]. Humans and livestock exposed to these high molybdenum intakes (10-15 mg/day in humans) displayed abnormally high levels of uric acid in serum and tissue xanthine oxidase activities. Increases in uric acid excretion were noted in some individuals but not when diets supplied less molybdenum (<1.5 mg/day). [Pg.499]

Specific Method for Determining Uric Acid in Serum Using High Perform- 2403. ance Liquid Chromatography and Gas Chromatography-Mass Spectrometry J. Chromatogr. 149 711-720 (1978) CA 89 38949s... [Pg.156]

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