University and Small

This was a national research program with research support for over 350 automotive suppliers, universities and small businesses. There were seven government agencies along with the United States Council for Automotive Research (USCAR) that joined with representatives from GM, Ford, and DaimlerChrysler. 

The Bayh-Dole Act, or the University and Small Business Patent Procedures Act, gives universities, small businesses, and nonprofit organizations the intellectual ownership of property, including new drugs, that they discover and develop with government funding. 

Birch Bayh, Democratic senator from Indiana from 1963 to 1981. With Republican senator Robert Dole, he cosponsored the Bayh-Dole Act of 1980 or the University and Small Business Patent Procedures Act, which gave universities and small businesses ownership of patents resulting from projects funded by the federal government. The major drug companies benefited as well They can license new drugs from the universities and small businesses that discovered them. 

The University and Small Business Patent Procedure Act, commonly known as the Bayh-Dole Act of 1980, gave nonprofit organizations such as universities as well as small businesses the right to retain patents for technology developed with government funds. 

Bayh-DoleAct (University and Small Business Patent Procedures Act). 1980.35 U.S.C. 200—212. 

OPTS (Optim i/.ed Potentials for Liquid Simulations) is based on a force field developed by the research group of Bill Jorgensen now at Yale University and previously at Purdue University. Like AMBER, the OPLS force field is designed for calculations on proteins an d nucleic acids. It in troduces non bonded in leraclion parameters that have been carefully developed from extensive Monte Carlo liquid sim u lation s of small molecules. These n on-bonded interactions have been added to the bonding interactions of AMBER to produce a new force field that is expected to be better than AMBER at describing simulations w here the solvent isexplic-... 

Supercomputers are found in many government research laboratories, intelligence agencies, universities, and a small number of industrial companies. In the United States, the National Science Foundation (NSF) has provided supercomputers to several prominent universities for both academic and industrial users. These centers provide state-of-the-art, supercomputer-tuned appHcations for a wide variety of disciplines, together with staffs who are very knowledgeable in optimization for supercomputer performance. 

The Big Bang Theory is the prevailing theory of the origin of the universe, and it is based on astronomical observations. According to this theory, about 15 billion years ago all the matter and energy in the visible universe was concentrated in a small, hot, dense region, which flew apart in a gigantic explosion. 

This universality is peculiar for the high-temperature approximation, which is valid for //J < 1 only. For sufficiently high temperature the quantum theory confirms the classical Langevin theory result of J-diffusion, also giving xj = 2xE (see Chapter 1). This relation results from the assumed non-adiabaticity of collisions and small change of rotational energy in each of them ... 

Both the heat and cold shock response are universal and have been studied extensively. The major heat shock proteins (HSPs) are highly conserved. They are involved in the homeostatic adaptation of cells to harsh environmental conditions. Some act as molecular chaperones for protein folding, while others are involved in the processing of denatured polypeptides whose accumulation would be deleterious. The cold shock results in the transient induction of cold shock proteins (CSPs), which include a family of small acidic proteins carrying the cold shock domain. The CSPs appear to be involved in various cellular functions such as transcription, translation and DNA recombination. 

For some polymers, like polystyrene or poly(methyl methacrylate), narrow standards of known molar mass and small polydispersity are commercially available, which can be used for calibration. Unfortunately, such standards are not available for all polymers and then the obtained true molar masses of a specific polymer might differ by a factor of two from the value obtained by calibration with, e.g., polystyrene [30] (see Section 9.1). This problem can be resolved by the so-called universal calibration, which is based on the finding that the retention volume of a polymer is a single-valued function of the hydrodynamic volume of the polymer, irrespective of its chemical nature and... 

Figure 9.3 The whole-body counter of University Medical Centre, Utrecht, The Netherlands. The counter has a mobile shadow shield with two Nal(Tl) scintillation detectors (4x6 in) placed at opposite sites of the subject. The lead shielding is 100 cm long with a diameter of 90 cm. The scanner moves on rails over a distance of 240 cm with an adjustable speed. Extreme variations in geometry yield practically the same value for 59Fe activity. The equipment can be used for measurements in man and small animals.

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