Tumor progression biology

Luan J, Shattuck-Brandt R, Haghnegahdar H, et al. Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. J Leukoc Biol 1997 62(5) 588-597. 

Jori, G. et al. (1984) In Vitro and In Vivo Studies on the Interaction of Hematoporphyrin and its Dimethyl Ester with Normal and Malignant Cells in Porphyrin Localization and Treatment of Tumors, Progress in Clinical and Biological Research, Vol. 170, pp. 471-482 (Doiron, D.R. and Gomer, C.J., Eds.) Liss, NY. 

Allavena, P., Marchesi, F., and Mantovani,A. (2005) The role of chemokines and their receptors in tumor progression and invasion Potential new targets of biological therapy. Curr. Cancer Ther. Rev. 1, 81-92. 

Glycoconjugates are the most functionally and structurally diverse compounds in Nature and it is now well established that protein- and lipid-bound saccharides play essential roles in many molecular processes impacting eukaryotic biology and disease.Examples of such processes include fertilization, embiyogenesis, neuronal development, hormone activities, the proliferation of cells and their organization into specific tissues. Remarkable changes in the cell-surface carbohydrates occur with tumor progression, which... 

Luan, J., Shattuck-Brandt, R., Haghnegahdar, H., Owen, J. D., Stricter, R., Burdick, M., Nirodi, C., Beauchamp, D., Johnson, K. N., and Richmond, A. (1997) Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. J. Leukoc. Biol. 62,588-597. 

The chemistry and biology of flavonoids is complex, and both beneficial and detrimental effects of flavonoids in mamnals have been predicted. Some of the reported cellular and biochemical effects of flavones and flavonols are summarized in Table 4. Many of the reported cellular effects of flavonoids could indirectly influence the biochemical processes related to ONA replication and/or tumor progression. 

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