Tumor growth retarding

Re has been incorporated into biodegradable microcapsules formed by polymerization of isobutylcyanoacrylate in the presence of 186Re dispersed in organic solvent. With a mean diameter of 10-15 pm these particles were used for radioembolization therapy of B16 melanoma induced in mice. More than 90% of the injected radioactivity was trapped within the tumors and tumor growth retardation was observed [157],... 

Inactivation of (he proteolytic activity had no influence on the antitumor activity, whereas peroxidase activity was necessary for tumor growth retardation. On the... 

Entin, I., Plotnikov, A., Korenstein, R. and Keisari, Y. (2003) Tumor growth retardation, cure and induction of antitumor immunity in B16 melanoma bearing mice by low electric field enhanced chemotherapy. Clin. Cancer Res. 9, 3190-3197. 

Lonnroth, C., Andersson, M., Lundholm, K. Indomethacin and telomerase activity in tumor growth retardation. Int. J. Oncol, 2001, 18, 929-937. 

The work of Ito and coworkers65 (Japan) on fibrosarcoma in mice showed that ECT retarded the tumor growth in mice the best results were obtained when ECT was preceded by a radiation treatment. 

In 2-year gavage studies there was some evidence of carcinogenic activity in male rats based on increased incidences of cholangiocar-cinomas and bile duct dysplasia and fibrosis. There was also some evidence of carcinogenicity in female mice based on increased incidences of hepatocellular adenomas. Male mice showed clear evidence of carcinogenicity based on increased incidences of hepatocellular adenomas and carcinomas. The development of liver tumors may be related to the chronic inflammatory effects noted at this site. In another experiment with hamsters, exposure to furfural vapor 7 hours/day, 5 days/week for 1 year caused irritation of the nasal mucosa and growth retardation but no evidence of carcinogenic effects. ... 

Prostaglandin TEI-9826 Fukushima et al. (2000) Emulsion formulation retarded tumor growth in mouse and rat models with sustained infusion... 

In mice bearing transplanted tumors, tumor growth was retarded 399... 

Use Selective biological stain for tumor cells, intra-vitam causes retardation of tumor growth. 

Use Biochemical research (inhibits tumor growth in rats and reversibly retards plant growth). 

Nijmegen breakage syndrome (NBS) is associated with defects in NBSl involved in homologous recombination. The patients display an excessively high risk for the development of lymphatic tumors, immunodeficiency, and chromosomal instabihty as well as microcephaly and growth retardation [77]. 

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