Trimethylene bis

Lindgren, P., Sundwall, A. 1960. Parasympatholytic effects of TMB-4 [1,1 -trimethylene bis (4-formylpyrldlnlum bromide)-dioxlme] and some related oximes in the cat. Acta Pharmacol. Toxicol. 17 69-83. 

Other flame-retardants selected as priority chemicals for the EU Risk Assessment process included tetrabromobisphenol A (TBBPA), hexabromocyclododecane (HBCD), tris(2-chloroethyl) phosphate (TCEP), tris (2-chloropropyl) phosphate (TCPP), tris(2-chloro-l-(chloromethyl)ethyl) phosphate (TDCP), and 2,2-bis(chloromethyl) trimethylene bis (bis(2-chloroethyl)phosphate) (V6). The flame-retardant synergist, antimony trioxide (Sb ), was also identified as a priority substance. Table 22.1 contains information on the EU Risk Assessments on the nine flame-retardants and one synergist. 

Curing of multicomponent systems consisting of BPA/DC, BMI and diallyl or triallyl esters (triallyl isocyanurate TAIC in particular) results in high Tgvalues. Such compositions consist of BPA/DC, BMI, TAIC, diallyl phthalate and dicumyl peroxide [127], BPA/DC prepolymer, BMI, TAIC, /erf.butyl peroxide, Zn acetate and DABCO [128] or BMI/trimethylene bis(4-aminobenzoate) prepolymer, BPA/DC, Zn octoate and TAIC [129]. 

Diperchlorate of N,fV -trimethylene-bis(3-fonnyl-5-methylsalicylaldehyde imi-nate)-dicopper was immobilized on polyvinylamine by the following scheme [22c] ... 

H. Schnutenhaus, and H. H. Brintzinger, 1, r-Trimethylene-bis(r 5-3-/t>/-/-butylcyclo-pentadienyl)titanium(IV) Dichloride, a Chiral mwa-Titanocene Derivative, Angew. Chem. Int. Ed. Engl. 18, 777-778 (1979). 

For the photodimerization of thymine, four isomeric products are assumed to be formed (Fig. 16). It is known that ds-syn and trans-syn isomers are formed by photolysis of l,l -trimethylene-bis-thymine, TpT, and denaturated DNA. The chemical shift of the 5-methyl proton at 1.12 to 1.18 ppm in our case suggests the formation of syn-type isomers. It has been found that when acetone is used as photosensitizer the products exhibit photodimer distribution similar to that obtained without using a sensitizer. 

Partial reduction of the trimethylene bis-pyridinium dication, J with the pyridinyl radical 4 yields the cation radical, In addition to modified pyridinyl... 

Trimethylene)bis(2,6-di-t-butylphenoxy) diradical 1018 Trimethylolphenol 627 Trimethylsilyloxydienes, in synthesis of phenols 441-443... 

Lead dioxide will oxidise 4,4 -(trimethylene)bis(2,6-di-t-butylphenol) leading to formation of a dispiro-compound by intramolecular cyclisation at the 4,4 -positions, and irradiation of this compound in a methylcyclohexane matrix at — 150°C gives 4,4 -(trimethylene)bis(2,6-di-t-butylphenoxy) diradical as a stable triplet species. Rose Bengal photooxidation of 2,3-dihydroxy-naphthalene and 2,7-dihydroxynaphthalene in basic aqueous solution gives the l,r-dimeric products by coupling of the radicals formed by electron transfer either to the excited sensitizer or to 02( Ag). ° The dimer which originates from 2,7-dihydroxynaphthalene is subject to further oxidation to 6,7-dihydroxyperylene-l,12-quinone. Irradiation of the dimethoxyphenol (82) under constant current electrolysis leads via (83) to formation of the substituted tricyclo[5.4.0.0 ]undec-8-ene (84) which can be converted into ( )-isoitalicene (85 R = Me, R = H). ... 

H25. Heilbronn, E., In vitro reactivation and aging" of Tabun-inhibited blood cholinesterase studies with N-methylpyridinium-2-aldoxine methane sulphonate and N,N -trimethylene bis (pyridinium-4-aldoxime dibromide). Biochem. Pharmacol. 12, 25-36 (1963). 

Bis(chioromethyl)trimethylene bis(bis(2-chloroethyl)-phosphate). EINECS 253-760-2 Phosphoric acid, 2,2-bis(chloro-methyl)-1,i propanediyi tetrakis(2-chloroethyl) ester. 

Treatment of LXXXV with ethyl formate gave the C-10 hydroxy-methylene derivative, which was converted to the thioketal LXXXVI by means of trimethylene-bis- -toluenethiosulfonate. Mercuric acetate in aqueous acetic acid furnished a bright yellow a-diketone, which formed the enol acetate (LXXXVII) on treatment with acetic anhydride in pyridine. Alkaline treatment of LXXXVII in the presence of air gave the tropolone LXXXVIII. Reductive removal of the sulfur atom with Raney nickel, saturation of the carbon-nitrogen double bond, and acetylation provided dLcolchiceine (LXXXIX), identical with an authentic specimen. 

N, N trimethylene bis (pyridine-4-aldoxime bromide) combined with benzactyzine... 

Draft EU risk assessments have been circulated for HBCD, TBBA, tris(2-chloroethyl) phosphate and the isopropyl equivalent, tris (2-dichlorethyl) phosphate and 2-2-bis(chloromethyl)trimethylene bis (bis(chloroethyl)phosphate), as well as medium-chain chlorinated paraffins. 

---