Tretinoin topical

Thalidomide (Thalomid) Topotecan (Hycamtin) Tretinoin, Topical [Retinoic Acid] (Retin-A, Avita, Renova, Retin-A Micro)... [Pg.39]

Embryotoxicity/teratogenicity is the major drawback in the therapeutic use of retinoids. The exposure of the fetus during the first trimester with oral retinoids is known to produce characteristic malformations.93 There have also been case reports about malformations associated with retinoid embryopathy after the mother had used tretinoin topically during the first trimester of pregnancy 94-96... [Pg.381]

Retinoids in Dermatology 13-Qs-retinoic acid (isotretinoin, Accutane ) is used orally, and all-trans-retinoic acid (Tretinoin ) topically, for treatment of severely disfiguring cystic acne. Etretinate (the trimethoxyphenyl analog of retinoic acid) and tazarotene (a receptor-specific retinoid) are used topically for the treatment of psoriasis. They are effective in cases in which other therapy has failed, and at lower levels than are required for the control of tumor development in experimental animals, although they have heen associated with hirth defects (Section 2.5.1.1 fohnson and Chandrarama, 1999). [Pg.72]

Topiramate, cognitive reactions, 26.81 Topoisomerase inhibitors, 21 All Topotecan, 21 All Trocetrapib, 32.816 Transfusions AIDS, 12.298 complications, 12.300 Tretinoin, topical, teratogenicity, 18.164 Triazolam, 16.33 Tricyclic antidepressants endocrine reactions, 11.12 mania, 13.8... [Pg.1121]

Tretinoin COOH Topical 0.025-0.1% Gels or creams Acne vulgaris, parakeratosis, hyperkeratosis Photoaging, actinic keratosis... [Pg.1074]

Patients of varying skin types (1-V) having striae distensae alba on the abdomen or thighs can apply topical 20% glycolic acid daily to the entire treatment area. In addition, these patients apply 10% L-ascorbic acid, 2% zinc sulfate, and 0.5% tyrosine to half of the treatment area and 0.05% tretinoin emollient cream to the other half of the treatment area. The creams are applied on a daily basis for 12 weeks. Improvement is evaluated at 4 and 12 weeks with increased elastin content within the reticular and papillary dermis [14]. [Pg.19]

Ash K, Lord J, Zukowski M, McDaniel DH (1998) Comparison of topical therapy for striae alba (20% glycolic acid/ 0,05% tretinoin versus 20% glycolic acid/ 10% L-ascorbic acid). Dermatol Surg 24(8) 849-856... [Pg.21]

Use of topical retinoids (tretinoin, tazaro-tene, retinol formulations) for 2-6 weeks prior... [Pg.26]

Photoaging also add topical tretinoin (0.025%) and topical bleaching agents (4% hydrochinone, 20% azelaic acid) for at least 2 weeks once a day (in the evening) to decrease the risk of post-inflammatory hyperpigmentation and promote wound healing... [Pg.32]

Use of topical retinoids (tretinoin, tazaro-tene, retinol formulations) for 2 to 6 weeks prior to peeling thins the stratum cornemn, reduces the content of epidermal melanin, and expedites epidermal healing. Retinoids also enhance the penetration of the peeling agent. They should be discontinued several days prior to the peeling procedure. Retinoids can be resumed post-operatively after all evidence of... [Pg.107]

Patient with mild acne treated with topical tretinoin... [Pg.124]

Topical tretinoin only partially effective even after 1 year of daily application [5]... [Pg.136]

Kimbrough-Green CK, Griffiths CE, Finkel LJ, et al (1994) Topical retinoic acid (Tretinoin) for melasma in black patients-a vehicle controlled clinical trial. Arch Dermatol 130 727-733... [Pg.159]

Griffiths CE, Finkel LJ, Ditre CM, et al (1993) Topical tretinoin (retinoic acid) improves melasma a vehicle-controlled, clinical trial. Br J Dermatol 129 415-421... [Pg.159]

Weinstein GD, Nigra TP, Pochi PE et al (1991) Topical tretinoin for treatment of photodamaged skin a multicenter study. Arch Dermatol 127 659-665... [Pg.174]

Griffiths CE, Kang S, Ellis CN, Kim KJ, Finkel LJ, Ortiz-Ferrer LC, White GM, Hamilton TA,Voorhees JJ (1995) IVvo concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation. A double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams. Arch Dermatol 131 1037-1044... [Pg.174]

Griffiths CEM, Goldfarb MT, Finkel LJ, et al (1994) Topical tretinoin (retinoic acid) treatment of hyperpigmented lesions associated with photoaging in Chinese and Japanese patients a vehicle-con-trolled trial. J Am Acad Dermatol 30 76-84... [Pg.174]

Tadaki T, Watanabe M, Kumasaka K, Tanita Y, Kato T, Tagami H, Horii I, Yokoi T, Nakayama Y, Kligman AM (1993) The effect of topical tretinoin on the photodamaged skin of the Japanese. Tohoku J Exp Med 169 131-139... [Pg.174]

Topical tretinoin a-hydroxy acid when reepithelialization is complete... [Pg.210]

Retinoids, which are highly effective in the treatment of acne, stimulate epithelial cell turnover and aid in unclogging blocked pores. Retinoids also exhibit anti-inflammatory properties through the inhibition of neutrophil and monocyte chemotaxis.8 Because of these comedolytic and antiinflammatory effects, topical retinoids are recommended as first-line treatment for mild to moderate comedonal and inflammatory acne.3 While success is seen with monotherapy, using a retinoid in combination with benzoyl peroxide or topical antibacterials is also an appropriate and effective therapeutic treatment option.3 Tretinoin, adapalene, and tazarotene are topical retinoids available for use in the treatment of acne. Table 62-2 describes the strengths and formulations of these agents. [Pg.963]

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