Post-inflammatory hyperpigmentation

Useful in acne, post-inflammatory hyperpigmentation and melasma... 

Most beneficial in treating recalcitrant melasma and post-inflammatory hyperpigmentation... 

Post-inflammatory hyperpigmentation more common than with salicylic acid peeling alone... 

Jessner s peels have been used to treat acne, melasma, post-inflammatory hyperpigmentation, lentigines, freckles, and photodamage (Figs. 3.2a,b, 3.3a, b and 3.4a, b). 

Fig. 3.3. a Patient with post-inflammatory hyperpigmentation, b Patient after treatment with a series of two Jessner s peels... 

Photoaging also add topical tretinoin (0.025%) and topical bleaching agents (4% hydrochinone, 20% azelaic acid) for at least 2 weeks once a day (in the evening) to decrease the risk of post-inflammatory hyperpigmentation and promote wound healing... 

Post-acneic disorders (post-inflammatory hyperpigmentation,erythema and shallow scars) (Fig. 5.3a, b)... 

Grimes et al. [8] reported substantial efficacy and minimal side effects in 25 patients treated with 20 and 30% salicylic acid peels in darker racial-ethnic groups. Conditions treated included acne vulgaris, melasma and post-inflammatory hyperpigmentation. 

Given these findings, indications for salicylic acid peels include acne vulgaris (inflammatory and non-inflammatory lesions), acne rosacea, melasma, post-inflammatory hyperpigmentation, freckles, lentigines, mild to moderate photodamage, and texturally rough skin. 

Fig. 10.1. a African American male with severe post-inflammatory hyperpigmentation, b Note significant improvement after combination salicylic acid/TCA peeling... 

In some patients, hyperpigmented macules may persist following resolution of inflammatory acne lesions. These dark areas have to be considered as healing lesions and not active acne. Post-inflammatory hyperpigmentation generally resolves, even if the resolution time may be very long. 

Fig. 13.3. a Forehead post-inflammatory hyperpigmentation, b Significant improvement in forehead hyperpigmentation following a series of glycolic acid 20-50% peels... 

Burns RI, Provost-Blank PC, Lawry MA, et al (1997) Glycolic acid peels for post inflammatory hyperpigmentation in black patients a comparative study. Dermatol Surg 23 171-174... 

In general, retinoids are also well tolerated in darker skin types however, retinoid dermatitis may cause post-inflammatory hyperpigmentation. In addition, progressive hyperpigmenta-... 

Complications of hydroquinone therapy include acute and chronic reactions. Common acute reactions are irritant and allergic contact dermatitis, and post-inflammatory hyperpigmentation. Lesional and perilesional hypopig-mentation may occur. This is usually a tempo-... 

Post-inflammatory hyperpigmentation (PIH) is the acquired presence of darker macules and patches of skin occurring at sites of previous cutaneous inflammatory conditions. The processes preceding the altered skin color include mechanical injuries, allergic reactions, primary inflammatory skin disorders, and therapeutic interventions. 

Fig. i6.i. Severe post-inflammatory hyperpigmentation caused by acne vulgaris... 

Fig. 16.2. a Post-inflammatory hyperpigmentation from acne vulgaris, b After a series of salicylic acid peels and hydroquinone 4%... 

Fig. 16.3. a Severe recalcitrant post-inflammatory hyperpigmentation secondary to acne excorians. b After a series of four salicylic acid 20 and 30% peels and 10% hydroquinone cream... 

Fig. 16.4. a Post-inflammatory hyperpigmentation from unknown topical irritant, b Cleared after a series of two glycolic acid peels (20 and 35%)... 

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