Treatment of Lung Cancer

Similarly, it is not possible at present to predict which tumours will respond to RT. Patients with lung cancer receiving RT will have a dose of RT based on, amongst other things, the size of the tumour, the patient s general health, and the localization of the tumour. Furthermore, RT is also associated with side effects. Therefore, S-FTIR spectroscopy could also be used to assess tumour cell resistance or sensitivity to RT. In this way, clinicians could deliver doses of RT based on S-FTIR spectroscopy data which would lead to an increase in the benefits of RT and a decrease in the side effects. This is known in clinical practice as the therapeutic index or ratio (the amount of a therapeutic agent that causes a therapeutic effect in relation to the amount that causes toxic effects). 

Parkin, F. Bray, J. Ferlay and Pisani Paola, Global Cancer Statistics, 2002, CA Cancer J. Clin., 2005, 55, 74—108. 

World Health Organization. Gender in lung caneer and smoking research. 2004 (http //www.who.int/gender/documents/en/lungcancerlow.pdf). 

Tyczynski, F. Bray and D. M. Parkin, Lung cancer in Europe in 2000 epidemiology, prevention, and early detection. Lancet Oncol., 2003, 4, 45-55. 

George and S. Spiro, Early Lung Cancer screening and detection. Primary Care Resp. J., 2006, 15, 332-336. 

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Ueoka H, Ohnoshi T, Kimura I. (1992) New anthracycline analogues in the treatment of lung cancer (in Japanese). Gan To Kagaku Ryoho 19 2146-2149. 

Fowler WC, Langer CJ, Curran WJ, et al. Postoperative complications after combined neoadjuvant treatment of lung cancer. Ann Thorac Surg 1993 55 986-989. 

Multimodality Treatment of Lung Cancer, edited by A. T. Skarin... 

Ipomeanol, a pneumotoxic furan derivative produced by sweet potatoes (Jpomoea batatas) infected with the fungus, Fusarium solani, has been in clinical trials for the treatment of lung cancer. A number of other plant-derived agents were entered into clinical trials and were terminated due to lack of efficacy or unacc table toxicity. Some examples are acronycine, bruceantin, maytansine and thalicarpine. ... 

Gore ME, Calvert AH, Smith LE. High dose carboplatin in the treatment of lung cancer and mesothelioma a phase I dose escalation study. Eur J Cancer Clin Oncol. 1987 Sep 23[9] 1391-7... 

VINDESINE is given i.v. in a dose of 3 mg/ m once weekly in the treatment of lung cancer (not the type with small cells), malignant melanoma and acute lymphatic leukaemia in children. 

Kahalalide G (79), the linear peptide form of 78, has so far been found to be inactive in all bioassays. To date, 17 kahalalides have been isolated and characterized from Bryopsis sp., but 78 remains the only kahalalide to advance to clinical trials for the possible treatment of lung cancer, other tumors, and AIDS. °... 

HPD is a complex compound, heterogeneous and weakly reproducible. However, its tumor tropism has clearly been demonstrated [9,10]. The first clinical trials with HPD, and for the treatment of lung cancer, were repotted by Hayata et al. in 1982 [11]. 

Y. Hayata, H. Kato, C. Konaka, J. Ono, N. Takizawa (1982). Haematoporphyrin derivative and laser photoirradiation in the treatment of lung cancer. Chest, 81, 269-277. 

Multimodality Treatment of Lung Cancer, edited by A. T. Skarin Cytokines in Pulmonary Disease Infection and Inflammation, edited by S. Nelson and T. R. Martin... 

Khan N, Mukhtar H. Dietary agents for prevention and treatment of lung cancer. Cancer Lett. 2015 359 155-164. 

New technology opens up completely new possibilities to design 3D structures for medical applications. The hexagonal braiding technique developed by Schreiber et al. (2009) allows various shapes such as bifurcations or stent into the stent to be produced. Such braided multilayer structures create mechanically separated layers on the outside and an inner structure that facilitates, for example, a functional respiratory epithelium to be established and make it possible to maintain the mucociliary function of the stented area in treatment of lung cancer (PulmoStent, 2014). 

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