Of lung cancer

Stomach Cancer. Of all the cancers, that of the stomach causes the second largest number of deaths. Only lung cancer kills more men, and only breast cancer kills more women. Stomach cancer is a painful and debilitating way to die, and the link to nitrate in water that has been suggested is a serious matter. There... 

Effects of indoor air pollutants on humans are essentially the same as those described in Chapter 7. However, there can be some additional pollutant exposures in the indoor environment that are not common in the ambient setting. From the listing in Table 23-1, radon exposures indoors present a radiation hazard for the development of lung cancer. Environmental tobacco smoke has been found to cause lung cancer and other respiratory diseases. Biological agents such as molds and other toxins may be a more likely exposure hazard indoors than outside. 

TABLE 5.8(c) Case-Control Studies of Lung Cancer among Workers in the Printing Industry... 

It has been known for years that professional bus and truck drivers as well as railroad workers suffer a larger than average risk of lung cancer because of... 

Polycyclic aromatic hydrocarbons have been classified as human carcinogens because they induce cancers in experimental animals and because smoking and exposure to mixtures of chemicals containing polycyclic aromatic hydrocarbons in the workplace increase the risk of lung cancer in exposed individuals. In experimental animals, benzo(a)pyrene induces cancer in different organs depending on the route of administration.Furthermore, exposure to polycyclic aromatic hydrocarbons commonly occurs in occupations related to traffic (use of diesel engines in transportation and railways). 

Coggoii, D., Pannett, B., and Ache.son, E. D. (1984). Use of job-exposure matrix in an occupational analysis of lung and bladder cancers on the basis of death certificates. /. Natl. Cancer Inst. 72, 61-65. 

No immediate symptoms, but longterm risk of chest and abdominal cancers and lung diseases. 

Certain compounds of this type are potent carcinogens. One of the most dangerous is benzo[a]pyrene, which has been detected in cigarette smoke. It is believed to be a cause of lung cancer, to which smokers are susceptible. 

Nitrogen mustard is clinically used for the treatment of lymphomas and some forms of lung cancer. The major indication for mechlorethamine is Hodgkin s disease as a part of the MOPP regimen (mechlorethamine + vincristine (oncovin) + procarbazine + prednisone). The usual dose consists of 6 mg/m2 on days 1 and 8. This drug has pronounced hematological toxicity (myelo-suppression). 

Molecular epidemiological studies to assess the risk associated with metabolic polymoiphisms for cancers of head-and-neck and the lung have shown that the overall... 

---