Testing Toxicology , programs

The National Toxicology Program (NTP) reported on tests on mice and rats that there was an increase in the spontaneous incidence of benign tumors in male and female rats and an increase in malignant Hver and lung tumors in B6C3E1 mice. NTP concluded that these data demonstrated clear evidence of carcinogenicity in mice and female rats and some evidence in male rats (35). 

Subchronic OralToxicity Test with Coumarin in Rat, National Toxicology Program, Washington, D.C., 1981. 

Luster, M.I. et al., Development of a testing battery to assess chemical-induced immunotoxicity National Toxicology Program s guidelines for immunotoxicity evaluation in mice, Fund. Appl. Toxicol., 10, 2, 1988. 

Luster, M.L., Munson, A.E., Thomas, P.T., Holsapple, M.P., Fenters, J.D., White, K.L., Jr., Lauer, L.D., Germolec, D.R., Rosenthal, G.J. and Dean, J.H. (1988). Development of a testing battery to assess chemical-induced immunotoxicity National Toxicology Program s Guidelines for Immunotoxicity Evaluation in Mice. Fund. Appl. Toxicol. 10 2-19. 

NTP. 1990. Chemical status report produced from NTP chemtrack system. National Toxicology Program, Division of Toxicology Research and Testing. 

Kluwe WM, McConnell EE, Huff JE, et al. 1982. Carcinogenicity testing of phthalate esters and related compounds by the National Toxicology Program and the National Cancer Institute. Environ Health Perspect 45 129-133. 

Zeiger E, Haworth S, Speck W, et al. 1982. Phthalate ester testing in the National Toxicology Program s environmental mutagenesis test development program. Environ Health Perspect 45 99-101. 

NTP. 1995. Printed long term technical reports and short term toxicity study reports. National Toxicology Program. Management status report. Division ofToxicology research and Testing. National Institute of Environmental Health Sciences. July 7, 1995. 

Yoon JS, Mason JM, Valencia R, et al. 1985. Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ Mutagen 7 349- 367. 

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