Toxicological screening

Tobacco and alcohol use Diet and physical activity Toxicology screen... 

Berman E, Schlicht M, Moser VC, et al. 1995. A multidisciplinary approach to toxicological screening 1. Systemic toxicity. J Toxicol Environ Health 45 127-143. 

Appendix 1 List of Resources for Hazard and Toxicological Screening and Research... 

The officer testified concerning a 2-year period of probation during which Juarez continually used PCP, as evidenced by toxicological screening, a condition of probation. This information was introduced by the prosecution to show Juarez s awareness of PCP and its effect upon him. 

Urine toxicology screens from the mothers and infants were obtained during the labor and delivery and/or postnatal periods. 

For all 12 mother-infant pairs, either the mother or the infant s toxicology report was subsequently positive for PCP. In nine cases, the screens for both mother and infant were positive. In two cases, the mother s results were positive and the infant s were negative. In one case, the infant had a positive result while the mother s test was negative. Test sensitivity, specimen handling procedures, and delays in obtaining specimens undoubtedly contributed to the inconsistency in paired results. Cocaine, codeine, and glutethemide, in addition to phencyclidine, were identified in the urine toxicology screens of two mothers and their neonates. 

Identify the underlying cause of the seizures and correct the cause, if possible. Does the patient have any laboratory abnormalities Is there a positive toxicology screen for alcohol or drugs ... 

Kl, a 27-year-old woman, was admitted to the cardiology unit from the emergency department after she called 911 claiming that she had severe chest pain. Upon arrival in the ED it was noted that her blood pressure was slightly elevated at 143/92 mm Hg, and that she was diaphoretic. She was in otherwise good physical condition, with no previous cardiac history. After a urine toxicology screen was positive for cocaine she admitted that she had smoked several rocks of crack an hour prior to having the chest pain. She said she almost never uses crack, but she s currently really depressed because she has lost her job. 

Chemiak MG. 1988. Toxicological screening for organophosphorus-induced delayed neurotoxicity Complications in toxicity testing. Neurotoxicology 9 249-272. 

THC is detectable on toxicologic screening for up to 4 to 5 weeks in chronic users. 

When toxicology screens are desired, blood or urine should be collected immediately when the patient presents for treatment. 

Zbinden, G., Eisner, J. and Boelsterli, U.A. (1984). Toxicological screening. Regul. Toxicol. Pharmacol. 4 275-286. 

Hopper, D. (1986). Behavioral measures in toxicology screening. In Safety Evaluation of Drugs and Chemicals (Lloyd W., Ed.). Hemisphere Publishing, New York, pp. 305-321. 

Other biological tests (e.g., endocrine, toxicology screen)... 

EPA. 1986c. Final report on the evaluation of four toxic chemicals in an in vivo/in vitro toxicological screen Acrylamide, chlordecone, cyclophosphamide, and diethylstilbestrol. Research Triangle Park, NC U.S. Environmental Protection Agency, Health Effects Research Laboratory. EPA-600-1-86-002. 

Agu RU, Jorissen M, Kinget R, Verbeke N, Augustijns P (2002) Alternatives to in vivo nasal toxicological screening for nasally-administered drugs. STP Pharma Sci 12 13-22. 

Pelander, A. Ojanpera, 1. Laks, S. Rasanen, 1. Vuori, E. Toxicological Screening with Formula-Based Metabolite Identification by Liquid Chromatography/Time-of-Flight Mass Spectrometry. Anal. Chem. 2003, 75, 5710-5718. 

Cherniak MG Toxicological screening for organophosphoms-induced delayed neurotoxicity complications in toxicity testing. Neurotoxicology 2 9-271, 1988... 

Discovery Toxicology Screening Predictive, In Vitro Cytotoxicity... 

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