Toxic Section

As noted under Mechanisms of Toxicity (Section 4.2), nitrate and nitrite esters are vasodilators with resulting hypotension (Nickerson 1975). Therapeutic doses of nitroglycerin for relief of angina are associated with headaches of vascular origin. Both PGDN and the structurally related ethylene glycol dinitrate produce headaches in humans and methemoglobinemia and hypotension in rats (Andersen and Mehl 1979). 

CAUTION Selenium and its compounds are toxic (Section 2.3) carry out this and the following preparations in an efficient fume cupboard. 

Originally, the PEEP index was designed to assess industrial and municipal effluent toxicity (Section 3). Because the PEEP index formula can accommodate any number and types of bioassays, it could also be applied in other versatile ways (Section 8). 

As outlined in the toxicity section above the toxicological mechanism of action of nerve agents is based on the chemical reactivity of the nucleophilic leaving group. Therefore, metabolism in terms of degradation by hydrolysis and binding to proteins determines bioavailability and elimination processes thus regulating toxicity. 

Reports of signs and symptoms by patients such as noted in the Acute Toxicity section should be regarded as the onset of toxicity. Administration of anesthetics should be halted and proper supportive care initiated. Benzodiazepines can be given prophy-lactically to prevent or decrease the expected seizure activity. If seizures have begun, then benzodiazepines or fast-acting barbiturates such as pentothal can be given intravenously. 

Fitzpatrick et al. 1992), the results cannot be extrapolated to natural soils in view of the importance of organic carbon in determining the bioavailability of the toxicant (Sections 3.2.2 and 3.2.3). 

Definition of Toxic Section 2(g) of the FHSA defines the term toxic to include any substance which has the capacity to produce personal injury or illness to man through ingestion, inhalation, or absorption through any body surface. At 16 C.F.R. 1500.3(c)(2), CPSC regulations elaborate on this definition as follows ... 

Definition of Highly Toxic Section 2(h)(1) defines the term toxic to include any substance which ... 

Jeffords/ Lieberman/ Collins Clean Power Act S.366 1.51 million ton cap by 2009 2.255 million ton cap by 2009 5 ton cap by 2009. Each plant limited to 2.48 grams of mercury per 1000 megawatt hours, or less as determined by EPA 2.05 billion ton cap by 2009 No change to existing law No changes to visibility or air toxics sections of existing law... 

This chapter presents the toxicological evidence for lead as a potent reproductive and intrauterine developmental toxicant. Sections of the chapter deal with male and female gametotoxicity, embryotoxicity, fetotoxicity, and various gross indices of fetal injury such as spontaneous abortion, stillbirth, and neonatal survival. Prenatal developmental effects as they affect the whole organism are presented here, while prenatal effects on various systems and organs are discussed in system- and organ-specific chapters. For example, developmental neurotoxicity of lead as it occurs in utero is discussed in Chapter 12. 

Revise the air toxics section, establishing a new program of technology-based standards and addressing the problem of sudden, catastrophic releases of toxics. 

Regional Lead Contact US. EPA Region 10 Toxics Section WCM-128 1200 Sixth Avenue Seattle. WA 98101-1128 (206) 553-1985... 

The simplest /3-dicarbonyl compound, propanedial (malondialdehyde, MDA), is a natural by-product of both oxidative and photochemical degradation of biological molecules. It is also highly toxic (Section 22-9) MDA is damaging to the eye, and failure of natural processes to clear it from the retina is the root cause of age-related macular degeneration, a leading cause of blindness in the elderly. 

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