Toluene p-bromo

Thionyl chloride, 55, 27 Thiophenol, 58, 144 Thiophenol, copper(I) salt, 55, 123 Thiophenol, lithium salt, 55, 122 Toluene, 56,86,58,125 Toluene, p-bromo-, 56, 86 Toluene, 4-bromo-, 55,49 Toluene, p-chloro-, 56, 86 Toluene, a-cyclohexyhdene-, 56, 105 Toluene, a (2 hydroxycyclohexyhdene)-, 56,105... 

Thiazoline, 2-methylthio- [Thiazole, 4,5-dihydro-2-(methylthio)-j, 82 2-Thiazoline, 2-(4-phenyl-l -bu ten-3-yl)thio-[Thiazole, 4,5-dihydto-2-[ [Mphenyl-methyl)-2-propenylj thio] -], 78 Thiazolium,7V-methyl-2-methylthio-, iodide [Thiazolium, 4,5-dihydro-3-methyl-2-(methylthio)-, iodide], 80 Thioacetic acid, trifluoro-, S-ethyl ester [Ethanethioic acid, trifluoro-,5-ethyl ester], 125 Toluene [Benzene, methyl-], 85 Toluene, p-bromo- [Benzene, l-bromo-4-methyl-], 86... 

Equip a 1 litre three-necked flask wdth a reflux condenser, a mechanical stirrer, and a cork carrying a dropping funnel and a thermometer which reaches nearly to the bottom of the flask connect the upper end of the condenser to an absorption trap (Fig. II, 8, 1). Place 100 g. of p-bromo-toluene (Section IV.62) in the flask and immerse the latter in an oil bath (colourless oil in a large beaker). Heat the bath until the temperature of the stirred p-broniotoluene reaches 105°. Illuminate the liquid with... 

In addition to the previously noted heterocycle syntheses under ring assembly, reaction of a cationic P-bromo-1 -aryl-2,3-dihydro-1.3.2-di i/ iphoxphininiiim salt 28 (X=Br) with sodium hydroxide in toluene gave the corresponding P-hydroxy derivative (see Sect. 4.3) [89],... 

A 50-ml Schlenck tube equipped with a stirring bar containing bis(l,5-cyclooc-tadiene)-nickel(O) (4.48 mmol), 2,2 -bipyridyl (4.48 mmol), and 1,5-cycloocta-diene (4.48 mmol) was treated with 5 ml of DMF and the ensuing deep blue/ purple solution stirred at 60°C for 30 minutes. The mixture was then treated with 2,7-diiodo-9,9-bis(2-ethylhexyl)fluorene (1.68 mmol) and 2,5-bis(p-bromo-phenyl)-A-(p-hexylphenyl)pyrrole (0.56 mmol) in 20 ml of toluene by syringe and then stirred for 5 days at 75°C. The solution was cooled to ambient temperature and precipitated into a mixture of 100 ml apiece of methanol and acetone and 5 ml concentrated hydrochloric acid. After of the mixture was stirred for 2 hours, it was filtered the solid residue was dissolved in chloroform and re-precipitated in methanol and acetone solution, and re-filtered. The residue was successively washed with methanol, water and methanol, and dried the product was isolated having a Mj, of 47,200 daltons. 

Two Pd(0)-catalyzed coupling reactions are reported for the synthesis of dialkyl 2-(ethoxycar-bonyl)vinylphosphonates. Thus, alkenyl triflates in DMF at room temperature and p-bromo acrylates in toluene at 80°C undergo very facile and efficient Pd(PPh3)4-catalyzed coupling with dialkyl phosphites to provide alkenyl phosphonates in high isolated yields (87-90%, Scheme 8.52). ... 

When toluene (9.5 g) is treated with dioxan Br2 (from 15.1 g of bromine) and heated at 35-40°, the mixture is rapidly decolorized after dilution with 10% NaOH solution,p-bromo-toluene (16.8 g) is obtained. Naphthalene can be similarly monobrominated at the 1-position, anthracene at the 9- and fluorene at the 2-position. 

Benzyl bromide Toluene, a-bromo- (8) Benzene, (bromomethyl)- (9) (100-39-0) (S)-2-(N,N-Dlbenzylamino)-3-phenyl-1-propanol Benzenepropanol, p-[bis(phenylmethyl)amino]-, (S)- (12) (111060-52-7)... 

The unsaturated nucleoside (53) has been prepared in good yield by electrochemical elimination from either the 2 -bromo-arabino- or the 3-bromo-xylo-nucleoside indicated in Scheme 14 however, the electrolyte can control the product obtained, for whereas 2-bromo-2 -deoxy-3, 5-di-O-propanoyl-uracil gave the 2, 3-unsaturated nucleoside in presence of tetraethylammonium toluene-p-sulphonate in methanol, with sodium acetate a mixture of products was obtained 3-deoxy-3-iodo-adenosine yielded 3-deoxy-adenosine (cordycepin) besides the 2, 3-unsaturated nucleoside.1-Acetyl-glycenose derivatives have been condensed with purine and pyrimidine derivatives in presence of antimony... 

Brown needles from AcOH. M.p. 173°. Distils undecomp, above 360°. Mod. sol. toluene. Spar. sol. hot EtOH. CrOg —> p-bromo- and p-nitrO benzoic acids. 

Protection and Deprotection.—N-Protected a-amino-acids are readily esterified by methanol or ethanol in 60—80% yield after reaction with an enamine (e.g. from isobutyraldehyde and piperidine) and t-butyl isocyanate. Such amino-acids can also be esterified efficiently with alkyl halides under phase-transfer conditions with no racemization. Direct esterification of a-amino-acids with ethyl toluene-p-sulphonate in boiling ethanol gives a-amino-acid ethyl esters in 80—90% yield as the sulphonate salts. The protection of acid functions by formation of the 2-chloro-(or bromo-)ethyl esters has been discussed. These derivatives survive exposure to both moderately acidic and basic conditions and are removable by conversion into the iodoethyl analogues followed by zinc reduction. Alternatively, they may be converted into hydrophilic ammonium or phosphonium salts which exhibit enhanced acid stability but which are cleaved by very dilute base. Yet another method for the removal of such groups using supernucleophilic Co phthalocyanin anions has been reviewed. Further routes to 2,2,2-trichloroethyl esters have been described, one of which employs an activated ester intermediate and is suited to acid-labile substrates. 

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