Toluene coordination, loss

Solvents acetone, methyl ethyl ketone (MEK), toluene, xylene, glycol, ethers, alcohol defats and dries skin some may be absorbed may carry other components through skin high volatility, exposure possible irritation central nervous system depression (e.g. dizziness, loss of coordination) low to high toxicity, longterm effects... 

Exposure to extremely high concentrations of toluene (5000-30,OOOppm) may cause mental confusion, loss of coordination, and unconsciouness within a few minutes. Controlled exposure of human subjects to 2 00 ppm for 8 hours produced mild fatigue, weakness, confusion, lacrimation, and paresthesias of the skin. At 600 ppm for 8 hours other effects included euphoria, headache, dizziness, dilated pupils, and nausea. At 800 ppm for 8 hours, symptoms were more pronounced and aftereffects included nervousness, muscular fatigue, and insomnia persisting for several days. " ... 

Use and exposure Technical grade dinitrotoluene is an oily liquid and easily combustible. Dinitrotoluenes are used primarily as chemical intermediates in the production of toluene diamines, diisocyanates, polyurethane foams, dyes, propellants, and polymers, and in the explosives industry." " " Toxicity and health effects Dinitrotoluene is known to cause adverse health effects on the blood, liver, kidney, and CNS in laboratory animals after an acute oral exposure. The animals also showed cyanosis and ataxia. Prolonged periods of exposure caused muscular weakness, poor muscular coordination, tremors, convulsions, ataxia, and paralysis. Industrial workers have developed headache, appetite loss, giddiness, dizziness, nausea, insomnia, and tingling pains in the extremities after chronic exposure to dinitrotoluene. - ... 

Recombination rates range from 10 to 10 M s, with similar values obtained by nanosecond measurements, whereas photodissociation yields are low and range from 0.03 -0.08. These low yields have been interpreted in terms of rapid relaxation of the photoexcited six-coordinate complex competing with ligand release. Other five-coordinate complexes are also formed on picosecond photolysis for example, a protoheme dimethyl ester bis(t-butyl isocyanide) in pure t-butyl isocyanide or in toluene. This photolysis results in the loss of one isocyanide ligand to produce an electronically excited five-coordinate complex, which decays to the ground state within 40 ps. The recombination rate for the formation... 

The equilibrium loss of dihydrogen from Ir(Pi-Pr3)2(r]2-H2)(H)2X complexes has been found to be strongly solvent dependent, as evidenced by the observation of vigorous effervescence when solid samples of Ir(Pz-Pr3)2(r 2-H2)(H)2X (X=C1, Br, or I) are dissolved in hydrocarbon solvents. Examination of the temperature dependence of the equilibria provided evidence that toluene reacts with all 3 five-coordinate species Ir(Pz-Pr3)2(H)2X,but that only the iodide complex interacted with alkane solvents. This conclusion was made based upon the smaller AH and AS values for the iodide complex equilibrium in alkane solvents, compared with the bromide and chloride complexes (Eq. 9) [47]. 

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