Tissue Engineering Agent

Silva et al. (2006) studied starch-based microparticles as a novel strategy for tissue engineering applications. They developed starch-based microparticles, and evaluated them for bioactivity, cytotoxicity, ability to serve as substrates for cell adhesion, as well as their potential to be used as delivery systems either for anti-inflammatory agents or growth factors. Two starch-based materials were used for the development of starch-based particulate systems (1) a blend of starch and polylactic acid (SPLA) (50 50 w/w) and (2) a chemically modifled potato starch, Paselli II (Pa). Both materials enabled the synthesis of particulate systems, both polymer and composite (with BG 45S5). A simple solvent extraction method was employed for the synthesis of SPLA and SPLA/BG microparticles, while for Pa and Pa/BG... 

Absorbable polyoxaesters containing pendant thio substituents, (IV), were prepared by the authors (4) and used in tissue engineering scaffolds and as drug delivery agents. 

Journal of Controlled Release. Amsterdam Elsevier Science Publishers. ISSN 0168-3659. Publishes broad spectrum of papers dealing with all aspects of controlled release and delivery, including gene delivery, tissue engineering, and diagnostic agents. 

Nanomaterials science for interfacing with living tissues, for delivery of pharmaceuticals, tissue-engineering scaffolds, wound repair, adhesion prevention, and other biological agents and medical devices. 

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