Thiamine hydrochloride vitamin

The quantitative analysis of thiamine hydrochloride (vitamin Bj), using HPTLC on silica gel plates with two different mobile phases, was elaborated.After TLC separation, vitamin Bj was derivatized by the use of ferf-butyl hypochlorite or potassium hexocyanoferrate (Ill)-sodium hydroxide as reagents. The ferf-butyl... 

Thiamine hydrochloride (vitamin Bi hydrochloride, HC12-H17ON4SCI2) is a weak acid with = 3.4 X 10. Suppose 3.0 X 10 g of thiamine hydrochloride is dissolved in 1.00 L of water. Calculate the pH of the resulting solution. [Hint This is a sufficiently dilute solution that the autoionization of water cannot be neglected.)... 

The dehydration of a thiamine hydrochloride (vitamin Bi) hydrate, commonly referred to as the monohydrate, was investigated by solid state NMR and X-ray diffraction. The hydrate was classified as a nonstoichiometric solvate since the water content depends on the water vapor pressure of the surrounding atmos-... 

Several reagents and reaction conditions such as TMSI (generated in situ from TMSCl and Nal), magnesium nitride (Mg3N2), triphenylphosphine (PPhs), thiamine hydrochloride (vitamin mnding under solvent-free conditions, PTSA with ultrasonic irradiation were recently reported to mediate efficiently the Hantzsch dihydropyridine synthesis. For instance, 1,4-dihydropyridines 143 were obtained in good yields using thiamine hydrochloride (vitamin B ) as the catalyst under solvent-free conditions at room temperature. ... 

Description of Method. The water-soluble vitamins Bi (thiamine hydrochloride), B2 (riboflavin), B3 (niacinamide), and Be (pyridoxine hydrochloride) may be determined by CZE using a pH 9 sodium tetraborate/sodlum dIhydrogen phosphate buffer or by MEKC using the same buffer with the addition of sodium dodecyl-sulfate. Detection Is by UV absorption at 200 nm. An Internal standard of o-ethoxybenzamide Is used to standardize the method. 

See also Vitamin Bi Thiamine deficiency, 26 291 Thiamine hydrochloride, 25 795 Thiamine hydrochloride... 

Stock solution 4. 100 x stock solution of vitamins was prepared by dissolving biotin (20 mg), folic acid (20 mg), pyrodoxine hydrochloride (100 mg), riboflavin (50 mg), thiamine hydrochloride (50 mg), nicotinic acid (50 mg), pantothenic acid (50 mg), vitamin B12 (1 mg), 4-aminobenzoic acid (50 mg) and thioctic acid (50 mg) in deionized water. The volume was adjusted to 1.0 L. The solution was filtered, sterilized and stored as 10 mL aliquots at —20 °C. 

Vitamin Bj or thiamine (Figure 19.21) is 3-(4-amino-2-methylpyrimidin-5-ylmethyl)-5-(2-hydroxyethyl)-4-methylthiazolium. It is isolated, synthesized, and used in food supplements and in food fortifications as a solid thiazolium salt in the form of thiamine hydrochloride or thiamine mononitrate [403]. 

The interaction of metal ions with vitamin Bi (thiamine hydrochloride, 135) continues to be of interest, and a combination of IR, XH and 13C NMR techniques have been applied to the... 

Aneurine Hydrochloride Thiamine Chloride Vitamin Vitamin Bi Hydrochloride... 

Vitamin Solution Dissolve 10 mg ofp-aminobenzoic acid, 8 mg of calcium pantothenate, 40 mg of pyridoxine hydrochloride, 4 mg of thiamine hydrochloride, 8 mg of niacin, and 0.2 mg of biotin in approximately 300 mL of water. Add 10 mg of riboflavin dissolved in approximately 200 mL of 0.02 N acetic acid. Add a solution containing 1.9 g of anhydrous sodium acetate and 1.6 mL of glacial acetic acid in approximately 40 mL of water. Dilute the solution with water to a final volume of 2 L. 

SYNS THIAMINE CHLORIDE HYDROCHLORIDE THIAMINE DICHLORIDE THIAMIN HYDROCHLORIDE THIAMINILLM CHLORIDE HYDROCHLORIDE USAF CB-20 VITAAEN B VITAMIN B HYDROCHLORIDE... 

Funk, W. Derr, P. Characterization and quantitative HPTLC determination of vitamin Bj (thiamine hydrochloride) in a pharmaceutical product. J. Planar Chromatogr. 1990, 3, 149-152. 

Thiamine Hydrochloride, USP. Thiamine hydrochlu-ride, thiamine monohydrochloride, thiamine chloride, vitamin B hydrochloride, vitamin B. aneurine hydrochloriile. occurs as small white crystals or as a crystalline powder. It has a slight, characteristic yeast-like odor. The anhydrous product, when exposed to air. rapidly absorbs about 4% of water. One gram is soluble in I mL of water and in about 100 mL of alcohol. It is soluble in glycerin. An aqueous solution. 1 20. has a pH of 3. Aqueous. solutions 1 100 have a pH of 2.7 to 3.4. Thiamine has pK values of 4.8 and 9.0. Thiamine hydrochloride is sensitive to alkali. The addition of 3 moles of sodium hydroxide per mole of thiamine h) dto-chloride gives the reaction shown on page 887. 

Thiamine hydrochloride absorption is sodium dependent thus, saturation limits ab.sorption to 8 to IS mg daily. Absorption is decreased in alcoholism and cirrhosis. Ftxxl affects the rate, but not the amount, absorbed. After absorption, thiamine hydrochloride is distributed to all tissues. There is limited storage of the vitamin in the body (about 30 mgl. Normally, little or no thiamine is excreted in the urine. If doses exceed physiological needs after body stores arc saturated, however, thiamine can be found in the urine as pyrimidine or as the unchanged compound. 

Thiamine Mononitrate, U5P. Thiamine mononitrate, thiamine nitrate, vitamin B mononitrate, is a colorless compound. It is soluble in water (1 35) and slightly soluble in alcohol 2% aqueous solutions have a pH of 6.0 to 7.1. This salt is more stable than the chloride hydrochloride in the dry state, less hygro.scopic, and recommended for multivitamin preparations and enrichment of flour mixes. 

Synonyms Vitamin Bj Aneurine hydrochloride Thiamine hydrochloride Thiadoxine Thiamin Vitamin Bj hydrochloride... 

Thiamine hydrochloride (C12H18ON4SCI2) is a water-soluble form of thiamine (vitamin Bi K. = 3.37X10 ). How many grams of the hydrochloride must be dissolved in 10.00 mL of water to give a pH of 3.50 ... 

Crystals, dec 196-200 Practically non hygroscopic. pKa 4.8. Soly in water 2,7 g/100 ml at 25° and approx 30 g/100 ml at lOCT. pH of 2% aq soln 6.5 to 7.1. Solns of pH 4.0 show greater stability than neutral solns and can be prepd in concns as high as 18.5 g/100 ml at room temp. For preparing solos of pH 4.0, approx 2.6 ml of I-ON HC1 is required For each gram of thiamine mononitrate when no other acidic or basic substances are present. One gram of thiamine mononitrate is equal to 343,000 international units. More stable than the chloride hydrochloride especially recommended for enrichment of flour mixes and prepn of multivitamin capsules and tablets. theraP cat Enzyme co-factor vitamin. thekap CAT (VET) See Thiamine Hydrochloride. 

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