The Reporting Period

Once a substance is listed for TSCA 8(d) reporting, existing studies are required to be reported within sixty days. The ITC will review the submitted information to assess whether test data are sufficient or whether a recommendation for testing should be made. If a study is initiated within the sixty day period, notification to EPA of study initiation must be provided. Upon completion of such an initiated study, the study must be submitted to the Agency within thirty days, regardless of the expiration of the initial sixty day reporting period.  

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Although the reporting period covers approximately 12 years, the most detailed reporting has been implemented by most of the licensees since 1984 when the new LER rule came into effect and fewer component failures were reported to the LER system. One should note that no human-error-related data are included in the data banlc except for actions that cause brolcen hardware. 

P. Somasundaran. Surfactant loss control in chemical flooding spectroscopic and calorimetric study of adsorption and precipitation on reservoir minerals—annual report for the reporting period September 30, 1992 to September 30, 1993. US DOE Fossil Energy Rep DOE/BC/14884-5, Columbia Univ, 1994. 

Several useful specialized reviews have appeared during the reporting period of this chapter. The chemistry of thienothiophenes <06AHC(90)125> and thienopyrimidines <06AHC(92)83> has been discussed in detail, whereas accounts of related interest highlight the field of thiaheterohelicenes <06OBC2518> as well as similar fused thiophene systems <06AG(E)8092>. 

The discrepancy between the number of well logs and the number of water chemistry results indicates that roughly 50% of well owners did not submit a water quality sample to the DENV for analysis and redeem their Water Quality Analysis Voucher over the reporting period. 

Existing chemical substances do not have to be notified. These are defined as those listed on the European Inventory of Existing Chemical Substances (EINECS) (a. 1), a list of approximately 100,000 substances reported as being supplied in the EU during the reporting period of 1 January 1971 to 18 September 1981 (389, 394). Also the DSD does not apply to medicinal products, cosmetic products, wastes, foodstuffs, pesticides, biocides and radioactive substances. 

Names missing in previous editions have been added now (also marked by an asterisk), explaining for literature citations older than the beginning of the reporting period (e.g., Ref. 8). 

Some flavone structures have been revised during the reporting period. The structure of 5,8,2 -triOH-6,7-diOMe flavone (compound 131 in Table 12.1) had been ascribed to a product isolated from Scutellaria baicalensis After synthesis, it needs to be revised to 5,7,2 -triOH-6,8-diOMe flavone (compound 132, Table 12.1). " Pedunculin, earlier isolated from Tithonia species and claimed as 5,8-diOH-6,7,4 -triOMe-flavone (compound 141, Table 12.1), needs to be revised, after synthesis, to 5,7-diOH-6,8,4 -triOMe flavone = nevadensin (compound 142 in Table 12.1). " In the previous review, the compound 5,6,7,4 -tetraOH-3, 5 -diOMe had erroneously been cited as a component of Artemisia assoana. Data have now been included for the correct structure, 5,7,4 -triOH-6,3, 5 -triOMe flavone (compound 251 in Table 12.1). A further flavone reported from Ageratum conyzoides (compound 263 in... 

With the exception of sanaganone, all other compounds listed in this section exhibit a chromeno-structure between 7-OH and C-6 of ring A, whereas the furano-substitution occurs on ring B. During the reporting period, only sanaganone is a newly described compound, occurring in the root bark of Millettia (Fabaceae). ... 

Some remarks should be made regarding structures revised during the reporting period. A flavonol isolated from Glycyrrhiza lepidota, named glepidotin, had been ascribed the structure of 8-C-prenylgalangin. ° Comparison with the synthetic product and its isomer revealed that it is, in fact, 6-C-prenylgalangin (compound 78, Table 12.4). Noricaritin... 

Periodic adverse experiences reports These reports must be submitted quarterly for the first 3 years after approval of the product (within 30 days of the end of the quarter) and annually (within 60 days of the anniversary of the approval date) thereafter. Periodic adverse drug experience reports should present a narrative overview and discussion of the safety information received during the reporting period. 

As described below, each of the three sections should identify all changes made during the reporting period,6 including those that were submitted in a PMA supplement or 30-Day Notice and those changes that you have not already reported in a PMA Supplement or 30-Day Notice.7... 

Information on Devices Shipped or Sold. To help the FDA assess the public health impact of the previously requested information, we are also asking that you provide us with data about the number of devices shipped or sold during the reporting period. For device implants, data regarding the number of devices actually implanted should be provided, if it is available. 

During the reporting period, the Board was informed of 31 shipments of P-2-P totalling 44.7 tons, which was almost four times the total amount reported for 2005. North America or West Asia was the intended destination of most of the shipments. As the experience of a number of countries, in particular in Europe, indicated that traffickers were continuing their search for P-2-P, the Board followed up with the importing... 

No mechanistic studies have appeared on the photochemistry of PCB mixtures or their congeners in water, the environmental liquid, during the reporting period. Several studies on the photochemistry of chlorobiphenyls in... 

It appears that only a limited number of studies are currently devoted to derivatives of the rather rare heterocycle selenophene. Therefore, it is not surprising that there is even less interest in tellurophene derivatives. Nonetheless, some potentially useful chemistry has emerged in this field during the reporting period of this chapter. 

Exposure of Bleached Pulp. Bleached pulp, based on 50% hardwood and 50% softwood kraft, jordaned to a Canadian standard freeness of 300-350 mL, was kindly supplied by Andrew Chase of the University of Maine. Unaged handsheets made from this pulp contained 85% a-cellulose (3) and 5% hot-1%-alkali-soluble matter (4). In the experiment illustrated in Figure 1, sheets were exposed in the Atlas 6500-W xenon-arc Fade-ometer equipped with Pyrex-glass filters the air temperature was 31 °C, and the relative humidity was 27% the black-panel temperature was 65 °C. Halfway through the reported period of... 

The progress in synthesis and chemistry of pyrroles, indoles, and related fused ring systems are the subjects of this chapter. Due to space limitations, only a selection of the recent advances reported during the period of January-December 2003 has been included in this text. However, several specialized reviews on the chemistry of indoles and pyrroles have appeared during the reporting period of this account, providing more in-depth coverage. 

In section 4, we turn our attention to the many applications of second order many-body perturbation theory in chemical modelling. We provide a brief S5mopsis of the applications of MP2 theory during the reporting period. 

Some progress has been made during the reporting period towards incorporating a description of correlation elfects in periodic solids using second order many-body perturbation theory. The aim research in this area is to provide a powerful and general-purpose computational tool, which can be used to study a variety of applications in condensed matter physics and solid state chemistry. 

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