Testosterone correlation between

There may be a significant negative correlation between endogeneous testosterone and Lp(a) levels in man (DIO), while, on the other hand, growth hormone treatment increases Lp(a) levels (E6, 02). 

One of the most interesting aspects of the changes in a-D-man-nosidase activity known to occur in vivo is the possible relationship with changes in zinc concentration in the tissues. In the case of rat epididymis, changes in enzyme activity have been monitored in parallel with measurements of zinc content.26 There was a positive correlation between the two variables, as both increased with age. The drop in a-D-mannosidase activity resulting from orchidectomy was accompanied by a 4-fold fall in the zinc content of epididymis, but the restoration of enzyme activity produced by subsequent injection of testosterone was not reflected in a detectable rise in the proportion of zinc. 

Figure 3 Correlation between the fraction absorbed and the membrane permeability in Caco-2 cells. Papp represents the membrane permeability of following 20 compounds, and was obtained by measuring the transcellular transport from the apical-to-basal side in Caco-2 cells. The fraction absorbed was obtained from literature. A amoxicillin, B antipyrine, C atenolol, D caffein, E cephalexin, F cyclosporin A, G enalaprilate, H L-glutamine, I hydrocortisone, J inulin, K D-mannitol, L metoprolol, M L-phenylalanine, N PEG-400, O PEG-4000, P propranolol, Q sucrose, R taurocholate, S terbutaline, T testosterone. Source From Ref. 37.

Figure 6 Correlation between testosterone 6P-hydroxylation and CYP3A protein levels, as determined by Western blot, in human hepatocytes incubated with several prototypical inducers.

Figure 9 Correlation between testosterone 6(3-hydroxylation and DFB debenzylation in various human liver microsomes. Abbreviation DFB, [3-[(3,4-difluorobenzyl)oxy]-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5//)-one]. Source From Ref. 32.

The determinants of F. have been subject to experimentation mostly in field and captive studies of ungulates. These support the expected association between the frequency and occurrence of Flehmen and the seasonality of reproduction. The elicitation of F. can also depend upon the social context presentation of urine or other stimuli alone may not produce consistent displays. When conspecific urine was tested out of context (i.e. no female present) in male Black-tailed deer, there was no discrimination between urine from individual adult males or between urine from estrous/non-estrous females (Altieri, 1980). Correlation of male endocrine status in reindeer (Rangifer tarandus) showed that the elevation of testosterone during rut and the duration of F. elicited by female urine was coincident F. bouts during rat were twice as long following exposure to adult female urine as to that of immature females (Mossing and Damber, 1981). 

The summary of Pe values for the steroids as a function of stirring rates is found in Table 11 and their correlations with log PC (n-octanol-water) in Figure 20. The transport kinetics of the relatively hydrophilic hydrocortisone and dexa-methasone are controlled by passive diffusion across the cell monolayer. On the other hand, the Pe values of testosterone and progesterone are highly dependent on stirring rate. The results for testosterone are used to obtain the relationships between the effective permeability coefficients of the ABL on the donor and receiver sides and the stirring rate, using the linear expression (see Eq. (69)]... 

Other reported adverse effects of gonadotropin treatment are headache, depression, edema, precocious puberty, and (rarely) production of antibodies to hCG. In men treated with gonadotropins, the risk of gynecomastia is directly correlated with the level of testosterone produced in response to treatment. An association between ovarian cancer, infertility, and fertility drugs has been reported. However, it is not known which, if any, fertility drugs are causally related to cancer. 

Salivary testosterone concentration correlates with free testosterone concentrations in plasma and has been advocated as an indicator of androgen status. In a multicenter evaluation that examined nine different laboratories using various RIA methods with and without extraction, good correlation was found between laboratories despite widely varying methods. Reference intervals of 4 to 14ng/dL and 2 to 6ng/dL have been reported for testosterone in saliva of men. Measurement of salivary testosterone in women has been less reliable, with no consensus on salivary concentrations available. However, one commer-... 

---