Teratocarcinoma cells: line

Bradley, A., Evans, M., Kaufman, M.H., and Robertson, E. (1984) Formation of germ-line chimaeras from embryo derived teratocarcinoma cell lines. Nature 309, 255-256. 

Andrews P W, Damjanov I, Simon D, et al. (1984). Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab. Invest. 50 147-162. 

Martin, G. R. and Evans, M. J. 1974. The morphology and growth of a pluripotent teratocarcinoma cell line and its derivatives in tissue culture. Cell 2(3) 163-72. 

Embryonal carcinoma cell lines have also been established in culture from transplantable teratocarcinomas. The embryonal carcinoma (EC) stem cells present in the tumors actually differentiated, and give rise to a variety of different types of embiyonic and adult cells. When these EC cells are cultured, they still possess the... 

Loric S, Maroteaux L, Kellermann O, Launay JM. Functional serotonin-2B receptors are expressed by a teratocarcinoma-derived cell line during serotoninergic differentiation. Mol Pharmacol 1995 47 458-466. 

A pluripotent human teratocarcinoma cell clone, NT2/D1, which was derived from the Tera-2 cell line, was induced to differentiate into cells with neuronal cell morphology by treatment with berberine. As early as one day after a 24 hour treatment of cells with berberine at a non-toxic dose of 0.1 mg/ml in culture medium, the cells began to show morphologic... 

A triorganotin quinolizidine compound, triethyitin Iupinyisulfide hydrochloride (Figure 4.4.7), has been reported to show quite good solubility in ethanol/water and to be a potent anti-proliferative against three different human cancer cell lines teratocarcinoma of the ovary (PA-1), colon carcinoma (HCT-8), and glioblastoma (A-172).2 The cytocidal effects due to this compound seem consistent with necrosis or delayed cell death rather than apoptosis. 

Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78 7634-7638... 

Recent studies by Prehm (1983a, b) have done much to solve the problems of hyaluronate chain assembly and in so doing, he has shown a new mechanism of saccharide synthesis, which may stimulate a re-evaluation of the supposed mechanisms by which some other polysaccharides are constructed. Using a line of teratocarcinoma cells (F9) in which the synthesis of hyaluronate could be induced with retinol, Prehm (1983a) examined the prop-... 

Robertson, E. J. (1987) Embryo-derived stem cell lines. In Teratocarcinomas and Embryonic Stem Cells, a Practical Approach (E. J. Robertson, ed.), pp. 71-112. IRL Press Oxford, Washington, DC. 

Chemical and physical analyses of the collagen isolated from cell lines derived from a mouse teratocarcinoma source or a mouse blastocyst source have identified a type V collagen, with distinct differences from types I, II, HI, and IV collagen. ... 

The two reporter cell lines used in these studies are derived from F9 teratocarcinoma cells and L cells. The F9 reporter cell line was established by transfection with a lacZ reporter gene construct and the L cell reporter line was established with luciferase as reporter gene. After selecting for the highest responders to retinoic acid (5 x 10" M), clonal cell lines were established and maintained under G418 selection. 

Lehman, J. M., Speers, W. C., Swartzendruber, D. E., and Pierce, G. B. 1974. Neoplastic differentiation Characteristics of cell lines derived from a murine teratocarcinoma. / Cell Physiol 84(1) 13-27. 

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