Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Cancer proteomics target discovery

Indeed, there are still many technological challenges to meet the needs for high sensitivity, reproducibility, and throughput required for successful target discovery in cancer proteomics, including ... [Pg.130]

High-throughput proteomic methods hold great promise for the discovery of novel protein biomarkers that can be translated into practical interventions for the diagnosis, treatment, and prevention of disease. These approaches may also facilitate the development of therapeutic agents that are targeted to specific molecular alterations in diseases such as cancer. In many cases, malignant cells yield unique protein profiles when total protein extracts from such cells are analyzed by 2-D gel electrophoresis or mass spectrometry (MS) methods. Such proteomic studies have the potential to provide an important complement to the analysis of DNA and mRNA extracts from these tissues.1... [Pg.335]

Krieg RC, Paweletz CP, Liotta LA, Petricoin EF 3rd. Clinical proteomics for cancer biomarker discovery and therapeutic targeting. Technol Cancer Res Treat 2002 1 263-272. [Pg.432]


See other pages where Cancer proteomics target discovery is mentioned: [Pg.3]    [Pg.426]    [Pg.263]    [Pg.11]    [Pg.198]    [Pg.200]    [Pg.282]    [Pg.299]    [Pg.398]    [Pg.264]    [Pg.736]    [Pg.660]    [Pg.513]    [Pg.149]    [Pg.558]    [Pg.141]    [Pg.212]    [Pg.225]    [Pg.49]    [Pg.128]    [Pg.1509]    [Pg.310]    [Pg.311]    [Pg.82]    [Pg.141]    [Pg.24]    [Pg.257]    [Pg.1115]   
See also in sourсe #XX -- [ Pg.130 ]




SEARCH



Cancer target

Proteomics cancer

Proteomics targeted

Target discovery

Target discovery targets

© 2024 chempedia.info