Tablets tragacanth

Nair and Chien [44] compared patches and tablets of different polymers (sodium carboxymethylcellulose, carbopol, polyethylene oxide, polymethyl vinyl ether-maleic anhydride, tragacanth) regarding their release characteristics of four drugs (chlorheximide, clotrimazole, benzocaine, and hydrocortisone). They observed sus-... 

Phenylis Salicylas, Phenyl Salicylate, Salol, C13H10O3, is the salicylic ester of phenyl, and occurs as a white, crystalline powder, odorless and almost tasteless, nearly insoluble in water, soluble in 10 parts alcohol, and very soluble in ether, chloroform, and oils. On warming with an alkali, it splits up into salicylic acid 60, and phenol 40, frequently repeated, in compressed tablets or in cachets, or suspended by mucilage of acacia or of tragacanth. 

Tragacanthin A complex mixture of polysaccharides containing some galacturonic acid residues The soluble component of the natural (plant origin) tragacanth gum Binder (in tablets) and demulcent... 

The stability of norfloxacin in suspensions prepared from two brands of film-coated tablets has been studied (12). The vehicle consisted of tragacanth, saccharin sodium, sorbitol solution, glycerol, parabens concentrate, peppermint spirit, purified water, and sjrup USP, yielding a final concentration of norfloxacin of 20 mg/ml. The resulting suspensions were chemically stable for 28 days when stored in amber glass bottles at room temperature. 

Tragacanth gum is also used similarly in cosmetics and food products, and has been used as a diluent in tablet formulations. 

Gum acacia and tragacanth are used in tablets, suppositories, vaginal jellies, and diabetic foods as excipients. A few cases of asthma have been reported to such vegetable gums (Gelfand 1943). Brown and Crepea (1947) reported a patient who was sensitive to tablets containing 0.005 mg tragacanth. 

Tragacanth is a natural gum obtained from the dried sap of several species of Middle Eastern or Mediterranean legumes (e g. Astragalus gummifer). Tragacanth is used as a food additive in cremes and toothpaste and also has medicinal application as a binder in tablets. It is a mild laxative. Xanthan gum is produced by fermentation of D-glucose with the microorganism Xanthomonas campestris. It is one of the most important microbial polysaccharides world production topped 50,0001 in... 

Sustained release tablets for metoprolol tartrate have been prepared using xanthan gum and tragacanth (38). 

Tragacanth was used along with pectin in sustained released matrix tablets produced by direct compression method. They showed good release retardation exhibiting a non-Fickian diffusion behavior [61]. Addition of tragacanth in a topical formulation resulted in acceleration of skin wound healing [63]. 

Powdered sugar and dextrose are aromatized, granulated with the addition of binding agents (fat, gelatine, gum arabic, tragacanth gum, starch) and lubricants (magnesium stearate), and tabletted under pressure. 

Recent studies evaluated Sesamum indicum L., sesame (Pedaliaceae) gum for its useful properties in the drug industry as a binder/hydrophilic polymer in the formulation of sustained release paracetamol granules and tablets, compared with standard binders Arabic gum, gelatin, and sodium carboxymethylcellulose [277] for the intestinal delivery of antifilarial drug diethylcarbamazine tablets [278] as an accessible, cost-effective and eco-friendly suspending agent in a pediatric pharmaceutical suspensions, compared with Arabic gum and tragacanth [279]. 

Divya P, Snehalatha, Bharathi DR, Naveen NR. Optimization of cross linked tragacanth and comparison of drug release rate profile with synthetic superdisintegrants on metoclo-pramide orodispersible tablets. Int J Pharm Life Sci. 4 (3) 2500-2505,2013. 

Storage Store in tightly closed containers in a cool, dry, and well-ventilated area away from oxidizing agents and sources of extreme heat Uses Protective colloid stabilizer, vise, control agent, thickener, emulsifier in cosmetics, foods, pharmaceuticals thickener for textile dyes textile coatings denture adhesive binder in paper mfg. pharmaceuticals (tablet excipient, bulk laxative) substitute for gum tragacanth... 

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