T cells and the cellular response

See also Ribonucleotide Reductase, The Immune Response, T Cells and the Cellular Response... 

See also Clonal Selection Theory, Antibody Structure, Generation of Antibody Diversity, Antibody Diversity (from Chapter 25) T Cells and the Cellular Response, AIDS and the Immune Response... 

Petrini, J. H., and Stracker, T. H. (2003). The cellular response to DNA double-strand breaks Defining the sensors and mediators. Trends Cell Biol. 13, 458-462. 

Morishita, M. Morimoto, E Kitamura, K. Koga, T Fukui, Y. Maekawa, H. Yamashita, I. Shimoda, C. Phosphatidylinositol 3-phosphate 5-kinase is required for the cellular response to nutritional starvation and mating pheromone signals in Schizosaccharomyces pombe. Genes Cells, 7, 199-215 (2002)... 

Immune responses have often been described in terms of humoral and cellular components. The humoral response involves the small circulating B lymphocytes (B cells), the antibodies (immunoglobulins), and proteins of the complement system. The cellular response is mediated by another group of small lymphocytes, the T lymphocytes (T cells). They resemble B cells in appearance but have quite different functions. However, newer knowledge has provided a somewhat different description of the body s defense... 

Inflammation is part of the first line response of the immune system to infection. Inflammation is characterized by two main components an exudative response and a cellular response. The exudative response involves the local recruitment of fluid (edema, swelling), containing proteins such as fibrin and immunoglobulins. The cellular response involves the release of cytokines from resident cells such as fibroblasts and the invasion of white blood cells into the inflamed tissue. Leukocytes take on an important role in inflammation by clearing the site from bacteria and cellular debris. In chronic inflammation an increased extravasation of neutrophils, monocytes, activated T cells, and macrophages to the inflamed site will persist. 

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