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Swelling, Drug Release

6 Swelling, Drug Release. - Gelation of alginate by external Ba (or other [Pg.508]

Ghaemy M, Naseri M. Synthesis of chitosan networks Swelling, drug release, tmd magnetically assisted BSA separation using Fe304 nanoparticles. Carbohydr Polym. 2012 90(3) 1265—72. [Pg.108]

Tablet Disintegration, Swelling, Drug Release. - In the past few years, studies on polymer matrixes used as controlled release systems (matrix characterization and factors influencing the release process) have been the subject of intense research interest. Different approaches and techniques have been used to understand the release process, in an effort to achieve maximum pharmaceutical effectiveness of the incorporated drug. [Pg.494]

Keywords Hydrophilic polymers, polymer blend, swelling, drug release, matrices, compatibility, synergistic effect, ionic polymers... [Pg.23]

A simple example of gel formation is provided by chitosan tripolyphosphate and chitosan polyphosphate gel beads the pH-responsive swelling abihty, drug-release characteristics, and morphology of the gel bead depend on polyelectrolyte complexation mechanism and the molecular weight. The chitosan beads gelled in pentasodium tripolyphosphate or polyphosphoric acid solution by ionotropic cross-hnking or interpolymer complexation, respectively. [Pg.160]

P Colombo, R Bettini, P Santi, A De Ascentiis, NA Peppas. Analysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport. J Controlled Release 39 231-237, 1996. [Pg.482]

CK Sim, K Park. Examination of drug release from enzyme-digestible swelling hydrogels. Proc Int Symp Controlled Release Bioact Mater 16 219-220, 1989. [Pg.556]

Photoirradiation —> photoisomerization of azobenzene moiety —> change in swelling —> change in drug release... [Pg.561]

Nam KW, Watanabe J, Ishihara K (2004) Modeling of swelling and drug release behavior of spontaneously forming hydrogels composed of phospholipid polymers. Int J Pharm 275 259-269... [Pg.164]

Fig. 2. Schematic representation of the behavior of a one-dimensional swelling controlled release system. The water (W) penetrates the glassy polymer (P) to form a gel. The drug (D) is released through the swollen layer. Fig. 2. Schematic representation of the behavior of a one-dimensional swelling controlled release system. The water (W) penetrates the glassy polymer (P) to form a gel. The drug (D) is released through the swollen layer.
El Sherbiny IM, Lins RJ, Abdel-Bary EM, Harding DRK (2005) Preparation, characterization, swelling and in vitro drug release behaviour of poly [N-acryloylglycine-chitosan interpoly-meric pH and thermally-responsive hydrogels. European Polymer Journal 41 2584-2591. [Pg.260]

Katono, H., Maruyama, A., Sanui, K., Ogata, N., Okano, T., and Sakurai, Y. Thermo-responsive swelling and drug release switching of interpenetrating polymer networks composed of poly(acrylamide-co-hutyl methacrylate) and polyfacrylic acid). J. Controlled Release 1991,16, 215-228. [Pg.173]

Swelling sustained-release coating polymers such as Eudragit NE 30 D, i.e. poly(ethyl-acrylate-methylmethacrylate) [101,102] or Eudragit RS [90], lead to a delay in drug release which is dependent on the thickness of the coating since these films have slow rates of swelling. [Pg.166]

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Drug release

Swelling release

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