Surgical sutures, colorants

No coloi additive oi product containing one can be used in the aiea of the eye, in surgical sutures, or in injections, unless so stated. Also, no colorant can be used to color foods for which standards of identity have been promulgated under Section 401 of the Federal Food, Dmg, and Cosmetic Act, unless the use of added color is authorized by the standard. Colorants without restrictions can be used for coloring foods generally, in amounts consistent with good manufacturing practice. 

No color additive or product containing one can be used iu the area of the eye, iu surgical sutures, or iujections unless so stated. Colorants without restrictions can be used for coloring cosmetics generally, iu amounts consistent with good manufacturiag practice. 

Color additives are routinely added to medical devices such as surgical sutures, surgical cements, and contact lenses (32). Sutures are usually colored to make them more visible during survery and, depending on the appHcation, during removal of the suture after the sutured area has healed. Surgical cements, too, are colored to make them more visible during use (Table 4). 

Use Restrictions. There are numerous restrictions on the use of color additives. They caimot, for example, be employed to deceive the pubHc by adding weight or bulk to a product or by hiding quaUty. In addition, special permission is needed to use colorants or products containing them in the area of the eyes, in injections, in surgical sutures, and in foods for which standards of identity have been promulgated under Section 401 of the Eederal Eood, Dmg, and Cosmetic Act. 

Comments Indigo carmine is an indigoid dye used to color oral and topical pharmaceutical preparations. It is used with yellow colors to produce green colors. Indigo carmine is also used to color nylon surgical sutures and is used diagnostically as a 0.8% w/v injection. 

USE As dye in a functional kidney test in coloring nylon surgical sutures. As a reagent for the detection of nitrate, chlorate, and in testing milk. Approved by the FDA fnr use in food and ingested drugs Fed. Regist 48, 5252 (1982). 

Classification Anthraquinone color Empirical C28H2oN2Na208S2 Formula C28H20N2O8S2 2Na Properties M.w. 622.57 Toxicology TSCA listed Uses Colorant in cosmetics, surgical sutures Manuf./Distrib. Aldrich http //www.sigma-aldrich.com... 

Uses Colorant in cosmetics, pharmaceuticals (FDA delisted) colorant for surgical sutures... 

CAS 4403-90-1 EINECS/ELINCS 224-546-6 Synonyms Acid green 25 Alizarine cyanine green F Cl 61570 2,2 -[(9,10-Dihydro-9,10-dioxo-1,4-anthracenediyl) diimino] bis (5-methyl) benzenesulfonic acid disodium salt Classification Anthraquinone color Empirical C28H2oN2Na20sS2 Formula C28H20N2O8S2 2Na Properties Dullish blue-gm. m.w. 622.57 Toxicology Low skin toxicity may cause skin irritation and sensitivity TSCA listed Uses Colorant for pharmaceuticals and surgical sutures Use Level 0.6% max. (sutures)... 

Toxicology LD50 (oral, rat) 3660 mg/kg mod. toxic by ing. eye irritant TSCA listed Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of NOx Uses Colorant in external cosmetics, pharmaceuticals, surgical sutures, haptics,... 

Uses Colorant in cosmetics, surgical sutures dye for cotton textile dyeing and printing inks mfg. of indigo derivs., paints, analytical reagents... 

HMIS Health 1, Flammability 0, Reactivity 1 Storage Deliq. hygroscopic light-sensitive Uses Blueprint photography feed additive foods (anticaking agent, dietary supplement, nutrient, infant formulas) medicine colorant for surgical sutures... 

Uses Colorant in surgical sutures astringent, antimicrobial in cosmetics... 

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