Surface modification with poly ethylene

Teramura Y, Iwata H (2011) Improvement of graft survival by surface modification with poly (ethylene glycol)-lipid and urokinase in intraportal islet transplantation. Transplantation 91 271-278... 

Sakai H, Takeoka S, Park SI, et al. Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats. Bioconugate Chem 1997 8 23. 

The noncovalent adsorption of proteins by p.CP is experimentally simple, but suffers from the disadvantage that the attachment can be reversible by rinsing the pattern with certain buffers and detergents or replacement by other proteins in solution. Moreover, the orientation of the deposited protein is not controlled. Delamarche et al. proposed the use of stamps modified with poly(ethylene oxide) silanes.100 The modification was conducted by oxidation of the PDMS stamp and reaction with APTES to yield an amino-functionalized surface. The next step was the reaction with homobifunctional cross-linker BS3 to bind surface amino groups with poly(ethylene glycol) (PEG) chains (Fig. 14.10). 

Boric acid ester salts can be formed by reacting alcohols (including diols) with boric acid in the presence of alkaline metal salts. The surface modification of poly(vinyl alcohol) and poly(ethylene-co-vinyl alcohol) with boric acid and sodium hydroxide leads to... 

Surface modification with hydrophilic polymers, such as poly(ethylene oxide) (PEO), has been beneficial in improving the blo( compatibility of polymeric biomaterials. Surface-bound PEO is expected to prevent plasma protein adsoiption, platelet adhesion, and bacterial adhesion by the steric repulsion mechanism. PEO-rich surfaces have been prepared either by physical adsorption, or by covalent grafting to the surface. Physically adsorbed PEO homopolymers and copolymers are not very effective since they can be easily displaced from the surface by plasma proteins and cells. Covalent grafting, on the other hand, provides a permanent layer of PEO on the surface. Various methods of PEO grafting to the surface and their effect on plasma protein adsorption, platelet adhesion, and bacterial adhesion is discussed. 

Lee, S. Voros, J., An Aqueous-Based Surface Modification of Poly(dimethylsiloxane) with Poly(ethylene glycol) to Prevent Biofouling. Langmuir 2005, 21,11957-11962. 

Tan, K., Obendorf, S.K., 2006. Surface modification of microporous pol3furethane membrane with poly(ethylene glycol) to develop a novel membrane. Journal of Membrane Science 274, 150-158. 

Kung, I.M., F.F. Wang, Y.C. Chang and YJ. Wang, Surface Modifications of alginate/poly(L-lysine) microcapsular membranes with poly(ethylene glycol) and poly(vinyl alcohol), Biomalerials, 16 (1995) 649-655. 

Popat, K.C., Mor, G., Grimes, C.A., Desai, T.A., 2004. Surface modification of nanoporous alumina surfaces with poly(ethylene glycol). Langmuir 20, 8035—8041. 

Popat KC, Mor G, Grimes CA, Desai TA (2004) Surface modification of nanoporous alumina surfaces with poly(ethylene glycol). Langmuir 20(19) 8035-8041 Pope EA, Braun K, Peterson C (1997) Bioartificial organs I silica gel encapsulated pancreatic islets for the treatment of diabetes mellitus. J Sol-Gel Sci Tech 8(l-3) 635-639 Sakai S, Ono T, Ijima H, Kawakami K (2003) Proliferation and insulin secretion function of mouse insulinoma cells encapsulated in alginate/sol-gel synthesized aminopropyl-silicate/alginate microcapsule. J Sol-Gel Sci Tech 28(2) 267-272... 

Lee S, Voros J. An aqueous-based surface modification of poly(dimethylsiloxane) with poly(ethylene glycol) to prevent... 

Park et al. [44] modified a Pellethane surface with poly(ethylene glycol) (MW) = 1000, PEGlk carrying terminal hydroxyl, amino, and sulfonate groups, respectively, to reduce bacterial adhesion (Fignre 2.8). After modification, the authors measured the dynamic C A before and after hydration using the Wilhelmy plate method. 

Amiji M, Park K. Surface modification of polymeric biomaterials with poly(ethylene oxide), albumin, and heparin for reduced thrombogenicity. J Biomater Sci Polym Ed 1993 4(3) 217-34. 

M. Laliberte, J.C. Gayet, G. Fortier, Surface modification of horseradish peroxidase with poly(ethylene glycol)s of different molecular masses (Mr) relationship between the Mr of the poly(ethylene glycol) and the stability of horseradish peroxidase-poly(ethylene glycol) adducts under various denaturing conditions. Biotechnol. Appl. Bioc., 20 (3) 397-413,... 

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