Surface assisted laser desorption/ionization SALDI

An application of surface-assisted laser desorption-ionization (SALDI) method for practical, ultrahigh sensitivity detection of aromatic amines by GC-MS is reported. The prototype analytical device for trace detection of different organic compounds is created. [Pg.103]

Surface-assisted laser desorption/ionization (SALDI). SALDI is a matrix-free approach for the analysis of low-mass molecules. In this innovative approach, the sample solution is placed directly onto a solid surface prepared by depositing an active material, such as powdered graphite, active carbon, carbon nanotubes, or silica sol-gel, onto a suitable substrate (e.g., A1 foil or Cu tape) and bombarded with a laser beam [47,48,60]. [Pg.43]

Chen, Y.-C., Sun, M.-C. (2001) Determination of Trace Quaternary Ammonium Surfactants in Water by Combining Solid Phase Extraction (SPE) with Surface-assisted Laser Desorption/Ionization (SALDI) Mass Spectrometry. Rapid Commun. Mass Spectrom. 15 2521-2525. [Pg.47]

In 1998, surface-assisted laser desorption/ionization (SALDI) was reported to produce less background signals compared to matrix-assisted laser desorption/ ionization mass spectrometry (MALDI-MS) [54-56]. Due to its high heat conductivity and absorption coef-... [Pg.1186]

Wu, J.Y., Chen, Y.C. (2002) A novel approach of combining thin-layer chromatography with surface-assisted laser desorption/ionization (SALDI) time-of-flight mass spectrometry. Journal of Mass Spectrometry, 37,85-90. [Pg.1203]

Key words Surface-assisted laser desorption/ionization (SALDI), desorption ionization on porous... [Pg.243]

Matrix-free methods for LD/ionization MS that are espe-dally useful for the analysis of lower molecular mass polymers are desorption/ionization on silicon (DIOS) and surface-assisted laser desorption/ionization (SALDI) MS. A cocrystallization of matrix and analyte is not required and the absence of matrix signals allows the quantitative analysis of low-molecular-mass polymer ions. ... [Pg.99]

Liu Q, Xiao Y, Pagan-Miranda C, Chiu Y, He L (2009) Metabolite imaging using matrix-enhanced surface-assisted laser desorption/ionization mass spectrometry (ME-SALDI-MS). J Am Soc Mass Spectrom 20 80-88. doi 10.1016/j.jasms.2008.09.011... [Pg.420]

Watanabe T, Kawasaki H, Yonezawa T, Arakawa R (2008) Surface-assisted laser desorption/ ionization mass spectrometry (SALDI-MS) of low molecular weight organic compounds and synthetic polymers using zinc oxide (ZnO) nanoparticles. J Mass Spectrom 43 1063-1071. doi 10.1002/jms.l385... [Pg.420]

SALDI Surface-assisted laser desorption/ionization... [Pg.31]

Surface-assisted laser desorption/ionization is a laser-induced ionization method developed in parallel to the more well-known matrix-assisted laser desorption/ionization (MALDI) method. Using inorganic materials as energy-mediating media, it has been exploited as a possible alternative to MALDI, especially in small molecule detection (1—4). The most successful SALDI substrate was reported by Siuzdak and coworkers, in which a silicon surface of mesoporous features was used, commonly termed as... [Pg.243]

Matrix-assisted laser desorption/ionization (MALDI) is widely used for the detection of organic molecules. One of the limitations of the method is a strong matrix background in low-mass (up to 500-700 Da) range. In present work an alternative approach based on the application of rough matrix-less surfaces and known as surface-assisted laser desoi ption/ionization (SALDI), has been applied. [Pg.140]

The ionization methods reported for IMS included MALDI [41,76-80], Secondary Ion Mass Spectrometry (SIMS) [19, 81-86], Matrix-enhanced (ME)-SIMS [87, 88], Desorption Electrospray Ionization (DESI) [89-99], Nanostructure Initiator Mass Spectrometry (NIMS) [100-102], Atmospheric Pressure Infrared MALDI Mass Spectrometry (AP-IR-MALDI-MS) [103], Laser Ablation-inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) [104-106], Laser Desorption Postionization (LDPI) [107], Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI) [108, 109], and Surface-assisted Laser Desorption/ioniza-tion Mass Spectrometry (SALDI) [110-112], Another method was called probe electrospray ionization (PESI) that was used for both liquid solution and the direct sampling on wet samples. [Pg.405]