Antibodies to hepatitis B surface antigen

Test results, standards to be met. The residual moisture and other volatile substances shall not exceed 1.0 percent except that, (i) they. shall not exceed 1.5 percent for BCG Vaccine, (ii) they shall not exceed 2.0 percent for Measles Vims Vaccine Live, Measles Live and Smallpox Vaccine, Rubella Vims Vaccine Live, and Antihemophilic Factor (Human) (iii) they shall not exceed 3.0 percent for Thrombin and Streptokinase, and (iv) they shall not exceed 4.5 percent for Antibody to Hepatitis B Surface Antigen for the Reverse Passive Hemaglutination Test. ... 

Dervite I, Hober D, Morel P. Acute hepatitis B in a patient with antibodies to hepatitis B surface antigen who was receiving rituximab. N Engl J Med 2001 344(l) 68-9. 

FIGURE 40-2. Typical sustained response to IFN-y in a patient with chronic hepatitis B. ALT, alanine transaminase Anti-HBe, antibody to hepatitis B e antigen Anti-HBs, antibody to hepatitis B surface antigen HBeAg, hepatitis B e antigen HBsAg, hepatitis B surface antigen. 

Alimonos K, Nafziger AN, Murray J, Bertino JS Jr. Prediction of response to hepatitis B vaccine in health care workers Whose titers of antibody to hepatitis B surface antigen should be determined after a three-dose series, and what are the imphcations in terms of cost-effectiveness Chn Infect Dis 1998 26 566-571. 

Zebedee SL, Barbas CF, Horn Y, Human combinatorial antibody libraries to hepatitis B surface antigen, Proc. Natl. Acad. Sci. USA, 89 3175-3179, 1992. 

The sera of certain animal species contain substances which are not antibodies, although they bind to hepatitis B surface antigen. They are probably glycoproteins and can be selectively removed from sera by reaction with purified hepatitis B surface antigen. 

Conventional ion-selective electrodes have been used as detectors for immunoassays. Antibody binding measurements can be made with hapten-selective electrodes such as the trimethylphenylammonium ion electrode Enzyme immunoassays in which the enzyme label catalyzes the production of a product that is detected by an ion-selective or gas-sensing electrode take advantage of the amplification effect of enzyme catalysis in order to reach lower detection limits. Systems for hepatitis B surface antigen and estradiol use horseradish peroxidase as the enzyme label and... 

Yano, A., Maeda, E, and Takekoshi, M. (2004). Transgenic tobacco cells producing the human monoclonal antibody to hepatitis B virus surface antigen. J. Med. Virol 73 208-215. 

In most countries, people with a history of jaundice are excluded from the donor population. However, there is a substantial geographic variation in the prevalence and detection rate of hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C virus (HCV) in donors (9,10). In addition, the type of donor involved influences the risk commercial (paid) donors carry a much higher hepatitis risk than non-remunerated voluntary donors (11,12). 

The transmission of viral infections by immunoglobulins has occasionally been suspected. However, intravenous immunoglobulin preparations are considered relatively safe, and there are no reports of transmission of HIV or hepatitis B (44,101). This is probably because of the high degree of viral inactivation of the cold ethanol fractionation and the screening of every donation for several viruses, such as HIV and hepatitis B and C (85). Of 56 patients with autoimmune diseases who received 167 infusions of intravenous immunoglobulin, none developed antibodies to human immunodeficiency virus and hepatitis C virus or hepatitis B surface antigen (12). 

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