Supported liquid membranes carrier-mediated transport

Shukala JP, Kumar A, and Singh RK. Macrocycle-mediated selective transport of plutonium (IV) nitrate through bulk liquid and supported liquid membranes using dicyclohexano-18-crown-6 as mobile carrier. Sep Sci Technol 1992 27 447 65. 

Kopunec, R. and Thang, N.M., Carrier-mediated transport of rare earth elements through liquid membranes. IE. Transport of Sc, Y, Ce, Eu, Gd, Tm, Yb through supported liquid membrane containing DEHPA. J. Radioanal Nucl Chem., 1993, 170 51-66. 

The mathematical model described here has illustrated that electrochemical effects can significantly influence protein flux in an affinity-mediated transport system. The system considered consists of a supported liquid membrane containing a pH-sensitive monoclonal antibody as carrier and human growth hormone as permeant. On a microscopic scale, Donnan inclusion of the hormone can increase the flux of hormone into the membrane. This allows more complex to be formed and simultaneously generates a steep hormone concentration gradient which drives a greater flux of free hormone than would occur in the absence of inclusion. 

Chrisstoffels LAJ, de Jong F, Reinhoudt DN, Mechanistic studies of carrier-mediated transport through supported liquid membranes. In Bartsch RA, Way JD, Eds., Chemical Separations with Liquid Membranes, ACS Symposium Series 642. American Chemical Society, Washington, DC, 1996 Chapter 3 18-56. 

Facilitated or carrier-mediated transport is a coupled transport process that combines a (chemical) coupling reaction with a diffusion process. The solute has first to react with the carrier to fonn a solute-carrier complex, which then diffuses through the membrane to finally release the solute at the permeate side. The overall process can be considered as a passive transport since the solute molecule is transported from a high to a low chemical potential. In the case of polymeric membranes the carrier can be chemically or physically bound to the solid matrix (Jixed carrier system), whereby the solute hops from one site to the other. Mobile carrier molecules have been incorporated in liquid membranes, which consist of a solid polymer matrix (support) and a liquid phase containing the carrier [2, 8], see Fig. 7.1. The state of the art of supported liquid membranes for gas separations will be discussed in detail in this chapter. 

Singh, S.K., Misra, S.K., Sudersanan, M., Dakshinamoorthy, A., Munshi, S.K., Dey, P.K., Carrier-mediated transport of uranium from phosphoric acid medium across TOPO/n-dodecane-supported liquid membrane, Hydrometallurgy 87, 190, 2007. 

Mechanistic Studies of Carrier-Mediated Transport Through Supported Liquid Membranes... 

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