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Coupling Reaction with

An interesting coupling reaction with the diazonium salt derived from anthranilic acid leads to an excellent method for the preparation of dlphenic acid. The reaction occurs with cuprous salts in ammoniacal solution ... [Pg.596]

Another type of polyol often used in the manufacture of flexible polyurethane foams contains a dispersed soHd phase of organic chemical particles (234—236). The continuous phase is one of the polyols described above for either slab or molded foam as required. The dispersed phase reacts in the polyol using an addition reaction with styrene and acrylonitrile monomers in one type or a coupling reaction with an amine such as hydrazine and isocyanate in another. The soHds content ranges from about 21% with either system to nearly 40% in the styrene—acrylonitrile system. The dispersed soHds confer increased load bearing and in the case of flexible molded foams also act as a ceU opener. [Pg.417]

Another area of interest to the industrial sector is the development of a more efficient synthesis of biaryl compounds. This has been accompHshed using a Ni(II)-cataly2ed Grignard coupling reaction with an aryl haUde (86—89). [Pg.397]

Diazo Coupling Reactions. Alkylphenols undergo a coupling reaction with dia2onium salts which is the basis for the preparation of a class of uv light stabilizers for polymers. The interaction of orxv i -nitrobenzenediazonium chloride with 2,4-di-/ r2 -butylphenol results in an azo-coupled product (30). Reduction of the nitro group followed by m situ cyclization affords the benzottiazole (31) (19). [Pg.62]

The copper species formed depends on the solvent, and three different species were detected by F NMR, although the structure of each species was not elucidated [245 This copper reagent undergoes a variety of coupling reactions with aryl, alkenyl, allyl, and acetylenic halides [244, 245 (equation 162)... [Pg.709]

The perfluoroacetylenic copper compounds undergo coupling reactions with aryl iodides and provide a useful synthetic route to the perfluoroalkyl aryl alkynes [147, 255] (equation 170) Coupling of these copper reagents with the 1-iodo-perfluoroalkynes gives the perfluorodiynes [747 255] (equation 171)... [Pg.711]

An alumina-supported trifluoromethylthiocopper reagent gave improved yields of trifluoromethyl aryl sulfides in coupling reactions with this reagent [26 ] (equation 184). [Pg.715]

The von Richter cinnoline process was further extended to solid-phase synthesis. The route began from benzylaminomethyl polystyrene and the required diverse o-haloaryl resins represented by 21 were prepared from substituted o-haloanilines. A Pd-mediated cross-coupling reaction with 21 and the alkynes provided the alkynylaryl derivatives represented by alkyne 22. The von Richter cyclization reaction with hydrobromic or hydrochloric acid in acetone/HaO and cleavage from the resin occurred in the same step to furnish the cinnoline derivatives 23 in 47-95% yield and 60-90% purity (no yield reported for each entry). [Pg.542]

Aromatic carbon-heteroatom coupling reactions with participation and formation of heterocycles 98JCS(P1)2615. [Pg.203]

Arenediazonium ions 1 can undergo a coupling reaction with electron-rich aromatic compounds 2 like aryl amines and phenols to yield azo compounds 3. The substitution reaction at the aromatic system 2 usually takes place para to the activating group probably for steric reasons. If the para position is already occupied by a substituent, the new substitution takes place ortho to the activating group. [Pg.84]

Diazonium salts are important intermediates in organic synthesis, e.g. for the Sandmeyer reaction. The most important use is the coupling reaction with phenols or aromatic amines to yield azo dyes (see Diazo coupling). [Pg.88]

Arenediazonium salts undergo a coupling reaction with activated aromatic rings such as phenols and arylamines to yield brightly colored azo compounds, Ar—N=N—Ar. ... [Pg.944]

ADP (adenosine diphosphate) and ATP (adenosine triphosphate) are complex organic molecules (Fig. 17.9) that, in essence, differ only hy the presence of an extra phosphate group in ATP. In the coupled reaction with glucose, about 38 mol of ATP are synthesized for every mole of glucose consumed. This gives an overall free energy change for the coupled reaction of... [Pg.469]

Intermediate 8, the projected electrophile in a coupling reaction with intermediate 7, could conceivably be derived from iodolactone 16. In the synthetic direction, cleavage of the acetonide protecting group in 16 with concomitant intramolecular etherification could result in the formation of the functionalized tetrahydrofuran ring of... [Pg.234]

Z)-3-(Tributylstannyl)allylamine participates in a palladium-catalyzed cross-coupling reaction with 2-bromobenzaldehyde (73, R = H) to give 3//-2-benzazepine (75, R = H). A similar reaction with the corresponding acetophenone 73 (R = Me) produces 1 -methyl-3//-2-benzazepine (75 R = Me), whereas with ethyl 2-bromobenzoate (73, R = OMe), 3//-2-benzazepin-(12/7)-one (74) is formed.237... [Pg.223]

In a very recent study, it has been demonstrated116 that zinc 5,15-bis(3,5-di-tert-butylphenyl)-porphyrin (13) without any activating halogen atoms at the chromophore can be directly linked in a very simple oxidative coupling reaction with silver(I) hexafluorophosphate to a mixture of porphyrin dimers, trimers and tetramers. The separation of the product mixture was achieved by gel-permeation chromatography based on the molecular weights of the oligomers. The dimer when re-exposed to the same reaction conditions yielded 25% of the tetramer.116... [Pg.610]

Fig. 7-2. Potential energy E as a function of the reaction coordinate for reactions of the P-nitrogen of arenediazonium ions with nucleophiles yielding (Z)- and (is)-azo compounds, a) Reactant-like transition states (e. g., reaction with OH) b) product-like transition states (e. g., diazo coupling reaction with phenoxide ions product = cyclohexadienone-type o-complex (see Sec. 12.8). Fig. 7-2. Potential energy E as a function of the reaction coordinate for reactions of the P-nitrogen of arenediazonium ions with nucleophiles yielding (Z)- and (is)-azo compounds, a) Reactant-like transition states (e. g., reaction with OH) b) product-like transition states (e. g., diazo coupling reaction with phenoxide ions product = cyclohexadienone-type o-complex (see Sec. 12.8).
Most diazotized heteroaromatic amines undergo normal coupling reactions with common aromatic coupling components, as well as with CH acidic compounds (review Butler, 1975). [Pg.311]

Azo coupling reactions with phenol ethers give in some cases the expected arylazo-phenol ether. In others, however, hydrolysis of the ether bond is observed and the arylazophenol is isolated. This ambiguity has, to the best of our knowledge, never been investigated systematically. [Pg.317]

In addition to protons, other electrofugic leaving groups such as SO3 (i. e., anions of sulfonic acids), Cl, Br, I, C02, and others can also be displaced in azo coupling reactions with aromatic substrates. The mechanism of such substitutions is in principle the same as that of dehydrogenation (see Fischer and Zollinger, 1972). [Pg.319]

A further example of an azo coupling reaction with an activated methylene compound (12.91), followed by ring closure to give a pyridazine derivative (12.92) in good yield (66%) was decribed by Gewald and Hain (1984). The reductive treatments of 12.92 give the pyrrole compounds 12.93 and 12.94 in 70% yield (Scheme 12-45). [Pg.338]

Interesting regioselectivities have been known for more than 100 years for azo coupling reactions with aminonaphthol derivatives such as 6-amino-4-hydroxy-2-naphthalenesulfonic acid (12.136, y-acid), 7-amino-4-hydroxy-2-naphthalenesulf-onic acid (J-acid), and 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid (H-acid). They give two types of isomeric azo compounds depending on the pH-value of the... [Pg.351]


See other pages where Coupling Reaction with is mentioned: [Pg.505]    [Pg.230]    [Pg.98]    [Pg.493]    [Pg.617]    [Pg.715]    [Pg.129]    [Pg.68]    [Pg.17]    [Pg.347]    [Pg.127]    [Pg.127]    [Pg.171]    [Pg.251]    [Pg.531]    [Pg.549]    [Pg.776]    [Pg.383]    [Pg.96]    [Pg.153]    [Pg.317]    [Pg.318]    [Pg.319]    [Pg.324]    [Pg.341]    [Pg.344]    [Pg.351]    [Pg.352]   


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Acyloin coupling reactions with esters

Adenosine triphosphate, coupled reaction with glucose

Adenosine triphosphate, coupled reactions reaction with glucose

Alkenyl halides coupling reactions with sp3 organometallics

Alkoxides, coupling reactions with

Alkynes coupling reactions with alkenyl bromides

Allyl bromide coupling reaction with

Allyl iodide coupling reaction with

Allylboronates from Palladium-catalyzed Cross-coupling Reactions with Allyl Electrophiles

Aromatic cations, coupling reactions with

Aryl halides coupling reaction with

Aryl halides coupling reaction with alkenes

Aryl halides coupling reaction with organoboranes

Benzene, trichlorodialkylation coupling reactions with primary alkyl Grignard

Bromobenzene coupling reaction with

Butyl bromide coupling reaction with

Carbonylative Coupling Reactions with Organometallic Reagents

Catalytic asymmetric cross-coupling reactions with secondary alkyl halides

Chemical reaction with coupled heat and mass flows

Copper cross-coupling reactions with

Coupling Reactions of Areneboronic Acids or Esters with Aromatic Electrophiles

Coupling of Single Electron Transfer with Acid-Base Reactions

Coupling reaction with organocuprate

Coupling reaction with organocuprates

Coupling reaction with organocuprates E2 elimination reactions

Coupling reaction with organocuprates classification

Coupling reaction with organocuprates elimination reactions

Coupling reaction with organocuprates examples

Coupling reaction with organocuprates primary

Coupling reaction with organocuprates reduction

Coupling reaction with organocuprates secondary

Coupling reaction with organocuprates synthesis

Coupling reaction with organocuprates tertiary

Coupling reactions alkenes with organic halides (Heck

Coupling reactions with aryl compounds

Coupling reactions with carbene complexes

Coupling reactions with heteroaryl compounds

Coupling reactions with organometallic

Coupling reactions with organometallic reagents

Coupling reactions with supported ionic liquid

Coupling reactions with supported ionic liquid catalysts

Coupling reactions with unsaturated substrates

Cross coupling reactions aryl boronic acids with amines

Cross coupling reactions aryl halides with amines

Cross-coupling Reactions of Terminal Alkynes with Organic Halides

Cross-coupling reaction with allylic halides

Cross-coupling reaction with carbon nucleophiles

Cross-coupling reactions alkyl halides with Grignard reagents

Cross-coupling reactions reaction with epoxides

Cross-coupling reactions with

Cross-coupling reactions with alkyl halides

Cross-coupling reactions with alkynyl, alkenyl, and aryl halides

Cross-coupling reactions with heterocycles, reviews

Cross-coupling reactions with organic halides

Cross-coupling reactions with organometallic reagents

Diazomethane coupling reactions with

Diffusion coupled with interface reaction

Grignard reagents coupling reaction with bromobenzene

Grignard reagents coupling reactions with alkyl halides

Halides coupling reaction with

Halides coupling reaction with sp3 organometallics

Halides coupling reactions with primary alkyl Grignard

Halides coupling reactions with secondary and tertiary

Heck Reactions Combined with Other Cross-Coupling Processes

Heck coupling reactions vinyl ethers with aryl halides

Heterocyclic coupling reactions with alkenyl bromides

Intermolecular reactions, cross-coupling with alkenes

Ligand Coupling Reactions with Heteroatomic Compounds

Magnesium, alkynylhalocross-coupling reactions with vinyl iodides

Mediated Cross-Coupling Reactions (Written with Dr. Shashank Shekhar)

Metal-Catalyzed Coupling Reactions with Aryl Chlorides, Tosylates and Fluorides

Methane oxidative coupling reaction with

Methyl halide coupling reaction with

Methylene iodide, reaction with zinccopper couple and cyclohexene

Methylene iodide, reaction with zinccopper couple and cyclohexene Methylenetriphenylphosphine

Methylene iodide, reaction with zinccopper couple and cyclohexene in preparation of methylenecyclohexane

Organic halides coupling reaction with organoboron

Organic halides coupling reaction with organocuprates

Organoboron compounds metal-catalyzed cross-coupling reactions, with organic

Organomagnesium compounds coupling reactions with alkenyl halides

Organozinc compounds coupling reactions with alkenyl halides

Organozinc reagents coupling reactions with alkenyl halides

Organozinc reagents cross-coupling reactions with alkyl halides

Palladium-catalyzed cross-coupling with reactions

Phenoxides, coupling reactions with

Phenylacetylene, oxidative coupling reaction with sodium hypobromite

Pinacol coupling reactions with alkenes

Pinacol coupling reactions with alkynes

Pinacol coupling reactions with carbonyl compounds

Pinacol coupling reactions with ketones

Primary alkyl coupling reactions with alkenyl halides

Primary alkyl coupling reactions with aromatic halides

Processes Coupled with Interface Reactions

Processes with Coupled Homogeneous Reactions

Processes with coupled chemical reactions

Radicals, coupling reactions with alkyl halides

Radicals, coupling reactions with alkynes

Recent Advances in Copper-promoted C-Heteroatom Bond Cross-coupling Reactions with Boronic Acids and Derivatives

Reductive coupling reactions with alkenes

Silane coupling agents reaction with filler surfaces

Single coupling reactions with amines

Single coupling reactions with hydroxy compounds

Sonogashira coupling reactions with phenylacetylene

Spontaneous processes coupling with nonspontaneous reactions

Stationary coupling of chemical reactions with heat and mass flows

Stepwise Coupling Reaction with Two Different Electrophiles

Subject coupling reactions with organometallics

Suzuki coupling reactions aryl chlorides with phenylboronic acid

Synthesis coupling reactions with organometallics

Tertiary alkyl coupling reactions with alkenyl halides

The Heck Coupling in Combination with Other Reactions

The Kumada Reactions Nickel-Catalyzed Cross-Coupling with Grignard Reagents

The Negishi Reaction Palladium-Catalyzed Cross-Coupling with Organozinc Reagents

Two Species with Coupled Reactions

Unsaturated organic molecules, coupling reactions with

Vinyl halides coupling reaction with alkenes

Vinyl halides coupling reactions with

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