Superparamagnetic iron-oxide nanoparticles

Muller, K., Skepper, J.N., Posfai, M., Trivedi, R., Howarth, S., Corot, C., Lancelot, E., Thompson, P.W., Brown, A.P., and Gillard, J.H. (2007) Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages invitro. Biomaterials, 28 (9), 1629-1642. 

Figure 1. MSC accumulate within the scar area. MSC fed with superparamagnetic iron oxide nanoparticles and injected into the border zone of infarcted myocardinm migrate into the infracted area.

A. Petri-Fink, M. Chastellain, L. Juillerat-Jeaimeret, A. Ferrari, and H. Hofmann Development of functionahzed superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26, 2685-2694 (2005). 

Frederic T., Carsten E., and Anne M.H. Superparamagnetic iron oxide nanoparticles (SPIONs)-loaded Trojan microparticles for targeted aerosol delivery to the lung. Eur. J. Pharm. Biopharm. 86(1) (2014) 98-104. 

J.S. Weinstein, et al., Superparamagnetic iron oxide nanoparticles diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review, J. Cereb. Blood How Metab. 30 (1) (2010) 15-35. 

M.M. Lin, et al.. Development of superparamagnetic iron oxide nanoparticles (SPIONS) for translation to clinical applications, IEEE Trans. Nanobiosci. 7 (4) (2008) 298-305. 

Superparamagnetic Iron Oxide Particles and Ultrasmall Superparamagnetic Iron Oxide Nanoparticles 533... 

Morteza Mahmoudi, Abdolreza Simchi and Mohammad Imani. (2009). Cytotoxicity of Uncoated and Polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles, /. Phys. Chem. C, volume 113, Issue 22, pp 9573-9580. 

Mahmoudi, M., Simchi, A., Imani, M., Stroeve, R, and Sohrabi, A. Templated growth of superparamagnetic iron oxide nanoparticles by temperature programming in the presence of poly(vinyl alcohol). Thin Solid Films, 518(15), 4281 289 (2010). 

Juang, J.H., Wang, J.J., Shen, C.R., Kuo, C.H., Chien, Y.W., Kuo, H.Y., et al Magnetic Resonance Imaging of Transplanted Mouse Islets Labeled With Chitosan-Coated Superparamagnetic Iron Oxide Nanoparticles. Transpl. P. 42, 2104—2108... 

Zhang, B., Yang, B., Zhai, C.X., Jiang, B., Wu, Y.L. The role of exendin-4-conjugated superparamagnetic iron oxide nanoparticles in beta-cell-targeted MRI. Biomateiials 34, 5843-5852 (2013)... 

Taratula O, Garbuzenko O, Savla R, Wang YA, He H, Minko T (2011) Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes. Curr Drug Deliv 8 59-69... 

In the past two decades, iron oxide or superparamagnetic iron oxide nanoparticles (SPION, e.g., y-Fe Oj, FejO and associated compounds) have been actively studied for medical image, drug dehvery, and hyperthermia treatment purposes. SPION has... 

Lu Y Yin Y, Mayers BT, Xia Y. Modifying the surface properties of superparamagnetic iron oxide nanoparticles through a sol—gel approach. Nano Lett 2002 2 183-6. 

Panahifar A, Mahmoudi M, Doschak MR. Synthesis and in vitro evaluation of boneseeking superparamagnetic iron oxide nanoparticles as contrast agents for imaging bone metabolic activity. ACS Appl Mater Interfaces 2013 5 5219-26. 

Taylor EN, Kummer KM, Durmus NG, Leuba K, Tarquinio KM, Webster TJ. Superparamagnetic iron oxide nanoparticles (SPION) for the treatment of antibiotic-resistant biofihns. Small 2012 8 3016-27. 

Durmus NG, Taylor EN, Kummer KM, Webster TJ. Enhanced efficacy of superparamagnetic iron oxide nanoparticles against antibiotic-resistant biofilms in the presence of metabolites. Adv Mater 2013 25 5706-13. 

---