Sucrose esters, of fatty acids

Emulsifier 473 Sucrose esters of fatty acids 20 83rd mtg 884, p 16, 1997... 

Naoe et al. [239] used the sugar ester DK-F-110, a mixture of sucrose esters of fatty acids, as a nonionic surfactant along with isopropyl alcohol and hexane in a reverse micellar system to extract cytochrome C. This surfactant has a critical micellar concentration of 0.5 g/1 and HLB of 11. Aqueous phase pH was found to have a major role in the forward extraction and optimum extraction was achieved at pH 8.0. However, for optimum back extraction, addition of isopropyl alcohol at 20 vol.% was found to be very essential. Further, the esterification reaction rate of Rhizopus delemar lipase was found to be maximum in DK-F-110 systems and also higher than those obtained in AOT and lecithin-RMs at a water concentration of 0.25 mol l h... 

Alkylglycosides and sucrose esters of fatty acids 0.03%-0.5% Rat, 16HBE14o cells Calcitonin, glucagon, insulin, leptin, growth hormone erythropoietin C, G, H, I 1, 6, 10, 84-90... 

The Alkylglycosides (AGs) and Sucrose esters of fatty acids (SEFAs) are families of nonionic glycosurfactants that have been used for their ability to gently extract membrane proteins with a minimal loss of functionality. These compounds can be synthesized and purified economically, with a worldwide production of thousands of tons per year. Chemically, AGs and SEFAs are a group of uncharged amphipathic compounds that consist of an aliphatic hydrocarbon chain attached to a sugar moiety. Certain AGs and SEFAs such as dodecanoyl sucrose have enjoyed widespread use as food-grade emulsifiers and in cosmetic preparations. 

Sucrose Esters of Fatty Acids 28.5.3.1 Neat SEFA... 

E473 Sucrose esters of fatty acids Oil and polyhydric alcohol... 

Sucrose esters Sucrose esters of fatty acids. See Sucrose fatly acid esters... 

Sucrose esters of fatty acids CH20C0[CH2],CH3 Hy —Ov hoch o. H... 

The original preparation of sucrose esters of fatty acids involves the transesterification of a triglyceride molecule with sucrose in the presence of a basic catalyst at 90°C in Af,Af-dimethylformamide (DMF) as solvent (Fig. 7.3) [4]. 

Sucrose esters of fatty acids having 12 or more carbon atoms display surface active properties. Most of them are odourless and tasteless (or slightly bitter) allowing them to find applications both in food and personal care products [17]. Sucroesters were approved and freely permitted in Japan for use as food additives in 1959 for both their emulsifying ability and their heat stability. In addition, they are well known to protect food proteins from thermal denaturation and inhibit the growth of Escherichia coli and other bacteria. 

Sucrose ester of fatty acid Sucrose cocoate Sucrose tallowate Sodium citrate Propylene glycol Ethanol Water... 

Sucrose esters of fatty acids are readily hydrolysed to sucrose and their component fatty acids by the normal digestive enzymes, and show no evidence of toxicity. Consequently, they are of importance as food additives (8), and in cosmetics (9-10). Many other unique applTcations of sucrose esters have been recognised (11). 

It is a well-known procedure to use soap as a catalyst or as a miscibility promoting agent in preparing sucrose esters of fatty acids without a solvent. One of these is the microemulsion process for preparing sucrose esters,developed by Snell for the State of Nebraska. Soap also is deemed an essential part of... 

In our process, the polyols may be added to the reaction mixture as an aqueous solution. However, water is not an essential component of the mixture as it is in the microemulsion process for the preparation of sucrose esters of fatty acids,... 

The reaction velocity ceui be influenced significantly by the choice of the reaction temperature and quantity of soap, without the formation of too much of the anhydro-compounds. As the soap has to be eliminated from the reaction product after the reaction and especially when the reaction product is to be used directly without purification, the queintity of soap chosen preferably will be as low as possible. The reactions usually are carried out under an inert gas for the exclusion of oxygen. The reaction products can be purified by known methods, like the methods used for the purification of sucrose esters of fatty acids. 

Other new processes have involved modifications of the solvent evaporation method. To produce a more homogeneous emulsion and stabilize the protein, surfactants have been added to the protein phase. For example, researchers have claimed that the addition of hydrophobic ion pairs to the protein phase allows a more homogeneous mixture of the protein in the polymer phase and provides stabilization of the protein (M. C. Manning, personal communication, 1994). Reversed micelles (sucrose esters of fatty acids) stabilize ultrafine emulsions of the protein in the polymer phase and provide stabilization ofthe protein (Hayashi et al, 1994). In addition, the use of a multiphase encapsulation system may protect the protein from denaturation. One t q)e of multiphase system involves the suspension of... 

It is often claimed in the preamble of publications on sugar surfactants that a major benefit of these materials lies in their low toxicity. The increased use of such surfactants as food additives has led to a number of detailed investigations into the toxicology of sucrose esters by the World Health Organization (WHO). In particular, the sucrose esters of fatty acids and monoglycerides were reviewed in terms of their pharmacokinetics, pharmacodynamics, acute toxicity, and short- and long-term tolerability. This section summarizes and discusses some of the toxicity results from these reports (WHO Food Additive Series 10, 15, 35, and 40). 

Mitsubishi Institute Clinical and pharmacokinetic studies of sucrose esters of fatty acids (Ses) in human. Report No. 3B159. August 5, 1994 Yokohama, Japan. 

Mitsubishi-Kagaku Foods Corporation Study of sucrose esters of fatty acids laxative study of S-1170. Unpublished report dated March 29, 1996. (Submitted to JECFA by Mitsubishi Chemical Corporation, Tokyo, Japan). 

Mistubishi-Kasei Institute, 13-Week oral subacute toxicity study of sucrose esters of fatty acids in rats. Study 0L492. December 27, 1991, Yokohama, Japan. (1991). 

Trade Names Ryoto Sugar Ester ER-190 Ryoto Sugar Ester ER-290 Surfhope SE COSME C-2101 Surfhope SE COSME C-2102 Sucrose esters Sucrose esters of fatty acids. See Sucrose fotty acid esters Sucrose fatty acid esters... 

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